Results 1 to 10 of about 30,571 (234)

5-Aminolevulinic acid improves chicken sperm motility [PDF]

Animal Bioscience, 2021
Objective This study investigated the effects of 5-aminolevulinic acid (5-ALA) on the motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm. Methods The pooled semen from Barred Plymouth Rock males was used.
Shin Taniguchi, Zhendong Zhu, Mei Matsuzaki, Masaoki Tsudzuki, Teruo Maeda   +4 more
doaj   +4 more sources

Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]

Frontiers in Microbiology
Introduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang, Peng Yang, Peng Yang, Yutian Fan, Yajuan Zhao, Yan Yu, Xinping Yan, Lu Han, Xinqiang Song, An-dong Gong, An-dong Gong, An-dong Gong   +11 more
doaj   +2 more sources

Effect of 5-aminolevulinic Acid on Mitochondrial Activity

Frontiers in Bioscience-Scholar, 2023
Background: Mitochondrial dysfunction is considered an important mechanism in the pathogenesis of various diseases. Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5 ...
Yuliya V. Markina, Alexander M. Markin, Tatiana V. Kirichenko, Taisiya V. Tolstik, Vadim R. Cherednichenko, Diana G. Kiseleva, Alexander N. Orekhov   +6 more
doaj   +3 more sources

Photodynamic inactivation of Klebsiella pneumoniae biofilms and planktonic cells by 5-aminolevulinic acid and 5-aminolevulinic acid methyl ester [PDF]

Lasers in Medical Science, 2016
The treatment of Klebsiella pneumoniae, particularly extended-spectrum β-lactamase (ESBL)-producing K. pneumoniae, is currently a great challenge. Photodynamic antimicrobial chemotherapy is a promising approach for killing antibiotic-resistant bacteria ...
Han, L, Ishaq, HM, Lei, J, Liu, C, Nair, SP, Wang, L, Xu, J, Zhou, Y   +7 more
core   +5 more sources

Augmented 5-aminolevulinic acid derived photodynamic therapy

Brain and Spine, 2022
Objective: The 5-aminolevulinic acid (5-ALA) induced elevation concentration of protoporphyrin IX (PPIX) in glioma cells makes photodynamic therapy (PDT) of these tumor cells feasible. Previous experiments showed that additional administration of Ko-143, an ABCG2 inhibitor, may lead to a further elevation [for full text, please go to the a.m. URL]
K. Ott, E. Bunk, S. Schipmann, A. Gorji, W. Stummer, M. Schwake   +5 more
doaj   +3 more sources

5-Aminolevulinic acid fermentation using engineered Saccharomyces cerevisiae [PDF]

Microbial Cell Factories, 2019
Background 5′-Aminolevulinic acid (ALA) is widely used in the pharmaceutical industry, healthcare, and food production, and is a substrate for the biosynthesis of heme, which is required for respiration and photosynthesis. Enhancement of ALA biosynthesis
Kiyotaka Y. Hara, Masaru Saito, Hiroko Kato, Kana Morikawa, Hiroshi Kikukawa, Hironari Nomura, Takanori Fujimoto, Yoko Hirono-Hara, Shigeyuki Watanabe, Kengo Kanamaru, Akihiko Kondo   +10 more
doaj   +3 more sources

Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria

Frontiers in Genetics, 2022
Introduction: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an autosomal recessive disease characterized by a profound deficiency in ALAD, the second enzyme in the heme biosynthetic pathway, and acute neurovisceral attacks with abdominal ...
Erica Graff, Karl E. Anderson, Cynthia Levy, Cynthia Levy   +3 more
doaj   +1 more source

Photodynamic therapy of acne

Biomedical Photonics, 2023
Acne is one of the most common skin conditions in the world. A number of studies have shown that photodynamic therapy (PDT) is safe and effective for both inflammatory and non-inflammatory acne and can significantly improve skin conditions in this ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source

Photodynamic therapy of psoriasis

Biomedical Photonics, 2023
Photodynamic therapy (PDT) in the treatment of psoriasis remains the subject of much debate. There is no consensus in the scientific community about effective and safe PDT regimens for psoriasis.
E. V. Filonenko, V. Ivanova-Radkevich
doaj   +1 more source

Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]

PLoS ONE, 2014
Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto, Toshiyuki Ozawa, Kunio Awazu, Nobuhisa Ito, Norihiro Honda, Sohkichi Matsumoto, Daisuke Tsuruta   +6 more
doaj   +1 more source