Results 11 to 20 of about 30,571 (234)

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

open access: yesBiuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +1 more source

Clinical guidelines and expediency of using 5-aminolevulinic acid for intraoperative visualization of margins of malignant tumors of the oral cavity

open access: yesОпухоли головы и шеи, 2022
Introduction. Treatment of the oral cavity is an important problem of current oncology due to high morbidity and mortality reaching 43 % in 5-year period after diagnosis.
Yu. V. Alymov   +2 more
doaj   +1 more source

5‐Aminolevulinic Acid Dehydratase [PDF]

open access: yesEuropean Journal of Biochemistry, 1981
The thiophilic reagent 5,5′‐dithiobis(2‐nitrobenzoic acid) (Nbs2) reacts with four sulphydryl groups in native 5‐aminolevulinic acid dehydratase from bovine liver (groups I, II, III and IV). All four of these groups exhibit various degrees of half‐site reactivity.
J S, Seehra   +3 more
openaire   +2 more sources

5‐Aminolevulinic acid‐based photodynamic therapy [PDF]

open access: yesCancer, 1997
Photodynamic therapy (PDT) for cancer patients has developed into an important new clinical treatment modality in the past 25-years. PDT involves administration of a tumor-localizing photosensitizer or photosensitizer prodrug (5-aminolevulinic acid [ALA], a precursor in the heme biosynthetic pathway) and the subsequent activation of the photosensitizer
Qian Peng   +6 more
openaire   +3 more sources

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

open access: yesGels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole   +8 more
doaj   +1 more source

5-Aminolevulinic acid synthesis in Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 1989
A hemA mutant of Escherichia coli containing a multicopy plasmid which complemented the mutation excreted 5-aminolevulinic acid (ALA) into the medium. [1-14C]glutamate was substantially incorporated into ALA by this strain, whereas [2-14C]glycine was not. Periodate degradation of labeled ALA showed that C-5 of ALA was derived from C-1 of glutamate. The
J M, Li   +3 more
openaire   +2 more sources

Photodynamic therapy in the treatment of extramammary paget’s disease

open access: yesBiomedical Photonics, 2022
Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on the effectiveness of different methods, there is no single therapeutic approach to the treatment of patients ...
E. V. Filonenko, V. Ivanova-Radkevich
doaj   +1 more source

Beef‐Liver 5‐Aminolevulinic Acid Dehydratase [PDF]

open access: yesEuropean Journal of Biochemistry, 1972
Beef liver 5‐aminolevulinate dehydratase was purified 700‐fold by salt fractionation, heat treatment, gel filtration and ion‐exchange chromatography. The final product was homogeneous by electrophoretic, ultracentrifugal and immunological criteria and had a molecular weight, by the low‐speed equilibrium method, of 260000.
E L, Wilson, P E, Burger, E B, Dowdle
openaire   +2 more sources

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

open access: yes, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]

open access: yes, 1999
Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Baumgartner, Reinhold   +6 more
core   +1 more source

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