Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial pressure (MAP) < 60 mmHg is important, the incidence of MAP < 60 mmHg when using 5-ALA is unclear ...
Tomoaki Yatabe +8 more
doaj +1 more source
Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A. +3 more
core +2 more sources
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - In vivo experiments on the dunning rat tumor model [PDF]
Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX ( PPIX) in an in vivo tumor ...
Baumgartner, Reinhold +12 more
core +1 more source
Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core +1 more source
The current diagnosis of superficial bladder cancer must be reconsidered [PDF]
The high recurrence and progression rates in superficial bladder cancer are partially related to the deficiencies of the standard conventional diagnostic modalities.
Hofstetter, Alfons, Zaak, Dirk
core +1 more source
Systems metabolic engineering of Escherichia coli for hyper-production of 5‑aminolevulinic acid
Background 5-Aminolevulinic acid (5-ALA) is a promising biostimulant, feed nutrient, and photodynamic drug with wide applications in modern agriculture and therapy.
Wei Pu +13 more
doaj +1 more source
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Al-Batran, Salah +8 more
core +1 more source
Pain in photodynamic therapy [PDF]
Photodynamic therapy is a modern treatment with applications in several medical specialties, which has been intensely studied in the last years. The main indications in dermatology are actinic keratosis, superficial basal cell carcinoma and Bowen\u27s ...
Benea, Vasile +6 more
core +3 more sources
Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant +40 more
core +1 more source
Laser-induced generation of singlet oxygen and its role in the cerebrovascular physiology [PDF]
For over 55 years, laser technology has expanded from laboratory research to widespread fields, for example telecommunication and data storage amongst others.
Bragina, O. A. +7 more
core +2 more sources

