Results 31 to 40 of about 30,571 (234)

Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]

open access: yes, 2008
DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core   +1 more source

Fluorescence‐based discrimination of breast cancer cells by direct exposure to 5‐aminolevulinic acid

open access: yesCancer Medicine, 2019
Protoporphyrin IX‐fluorescence measurement is a powerful in situ approach for cancer detection after oral/topical administration of 5‐aminolevulinic acid.
Midori Morita   +8 more
doaj   +1 more source

Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]

open access: yes, 2002
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Al-Batran, Salah   +8 more
core   +1 more source

Neuroprotective effects of 5-aminolevulinic acid against neurodegeneration in rat models of Parkinson's disease and stroke

open access: yesJournal of Pharmacological Sciences, 2020
Oxidative stress is associated with the progression of the neurodegenerative diseases Parkinson's disease (PD) and cerebral ischemia. Recently, 5-aminolevulinic acid (5-ALA), an intermediate in the porphyrin synthesis pathway, was reported to exert ...
Masanori Hijioka   +6 more
doaj   +1 more source

Novel pathway for corrinoid compounds production in lactobacillus [PDF]

open access: yes, 2018
Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Font, Graciela Maria   +4 more
core   +2 more sources

Bioquímica e ação citotóxica de alfa-aminocetonas endógenas Biochemistry and cytotoxicity of alpha-aminoketones

open access: yesQuímica Nova, 2005
alpha-Aminoketones are expected to undergo enolization and subsequent aerobic oxidation yielding oxyradicals and highly toxic a-oxoaldehydes. Our interest has been focused on two endogenous a-aminoketones: 5-aminolevulinic acid (ALA) and aminoacetone (AA)
Fernando Dutra, Etelvino J. H. Bechara
doaj   +1 more source

5-Aminolevulinic acid: A matter of life and caveats

open access: yesJournal of Photochemistry and Photobiology, 2021
Our mini-review concerns the potential adverse pro-oxidant role of 5-aminolevulinic (ALA), the first protoporphyrin IX (PP-IX)/heme precursor widely used in commercial formulations for endogenous photodynamic therapy (PDT).
Etelvino J.H. Bechara   +2 more
doaj   +1 more source

A New Synthesis of 5-Aminolevulinic Acid.

open access: yesAgricultural and Biological Chemistry, 1991
(1991). A New Synthesis of 5-Aminolevulinic Acid. Agricultural and Biological Chemistry: Vol. 55, No. 6, pp. 1687-1688.
Hiroshi Kawakami   +2 more
openaire   +2 more sources

Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole compounds, with wide applications in medicine, agriculture and other burgeoning fields. Because of its potential applications and disadvantages of chemical synthesis,
Meiru Jiang   +5 more
doaj   +1 more source

Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]

open access: yes, 2008
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P.   +4 more
core   +1 more source

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