Results 51 to 60 of about 30,373 (230)

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

Identification of risk factors associated with oral 5-aminolevulinic acid induced adverse events in photodynamic diagnosis−transurethral resection of bladder tumor

Photodiagnosis and Photodynamic Therapy
Background: Oral 5-aminolevulinic acid for transurethral resection of bladder tumor reduces bladder cancer recurrence compared with standard white-light transurethral resection of bladder tumor.
Yu Okabe, Yuichiro Fukuhara, Wataru Matsuoka, Nobuyuki Nakamura, Hiroshi Matsuzaki, Takeshi Miyazaki, Naotaka Gunge, Kosuke Tominaga, Kazuna Tsubouchi, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga   +12 more
doaj   +1 more source

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +1 more source

Comparative experimental study of 5-ALA and 5-ALA hexyl ester specific activity

Biomedical Photonics, 2018
A comparative experimental study of the specific activity of drugs based on 5-aminolevulinic acid (5-ALA) and its hexyl ester (5-ALA HE) was carried out. Their ability to induce the synthesis of photoactive protoporphyrin IX in the healthy tissues of the
R. I. Yakubovskaya, A. A. Pankratov, E. V. Filonenko, E. A. Lukyanets, V. I. Ivanova-Radkevich, A. A. Trushin, A. D. Kaprin   +6 more
doaj   +1 more source

Derivatives of 5-Aminolevulinic Acid for Photodynamic Therapy

Perspectives in Medicinal Chemistry, 2007
Photodynamic therapy (PDT) is a clinical treatment that combines the effects of visible light irradiation with subsequent biochemical events that arise from the presence of a photosensitising drug (possessing no dark toxicity) to cause destruction of selected cells. Today, the most common agent used in dermatological PDT is 5-aminolevulinic acid (ALA).
Ryan F, Donnelly, Paul A, McCarron, A David, Woolfson   +2 more
openaire   +2 more sources

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins [PDF]

, 2011
Background: The Gram-negative bacterium Haemophilus influenzae is a glutathione auxotroph and acquires the redox-active tripeptide by import. The dedicated glutathione transporter belongs to the ATP-binding cassette (ABC)-transporter superfamily and ...
Vergauwen, Bjorn, Van der Meeren, Ruben, Dansercoer, Ann, Savvides, Savvas   +3 more
core   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

Photodynamic therapy of Bowen’s disease

Biomedical Photonics
Bowen’s disease is a form of non-invasive (in situ) squamous cell skin cancer localized in the non-genital area. Russian and European clinical guidelines include photodynamic therapy (PDT) in the standard of care for patients with Bowen’s disease. In the
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source

Photoactivable oxobenzopyranoxazole esters of 5-aminolevulinic acid [PDF]

, 2016
Comunicação em painel P51 no 1st European Young Chemists Meeting/ 5th Portuguese Young Chemists Meeting, Guimarães, Portugal, 26-29 Abril 2016.In this communication we report the synthesis of new oxobenzopyranoxazoles 1a,b as photolabile protecting ...
Costa, Susana P. G., Gonçalves, M. Sameiro T., Soares, Ana Maria Silva   +2 more
core