Results 81 to 90 of about 30,373 (230)

Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]

, 2014
Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia, Rivarola, Viviana, Rumie Vittar, Natalia Belen   +2 more
core   +1 more source

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

Photochemistry and Photobiology, EarlyView.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard, Meghan M. Dillon, Lauren A. Sapienza‐Lundie, Suzanne E. Fenton, Imran Rizvi   +4 more
wiley   +1 more source

Perspective review of what is needed for molecular-specific fluorescence-guided surgery [PDF]

, 2018
Molecular image-guided surgery has the potential for translating the tools of molecular pathology to real-time guidance in surgery. As a whole, there are incredibly positive indicators of growth, including the first United States Food and Drug ...
Achilefu, Samuel, Pogue, Brian W., Rosenthal, Eben L., van Dam, Gooitzen M.   +3 more
core   +4 more sources

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source

LCAA, a Novel Factor Required for Magnesium Protoporphyrin Monomethylester Cyclase Accumulation and Feedback Control of Aminolevulinic Acid Biosynthesis in Tobacco

, 2012
Low Chlorophyll Accumulation A (LCAA) antisense plants were obtained from a screen for genes whose partial down-regulation results in a strong chlorophyll deficiency in tobacco (Nicotiana tabacum).
Albus, C., Bock, R., Czarnecki, O., Grimm, B., Kahlau, S., Lein, W., Rothbart, M., Salinas, A., Schöttler, M., Thiele, W.   +9 more
core   +1 more source

Overview on topical 5-ALA photodynamic therapy use for non melanoma skin cancers [PDF]

, 2014
Ultraviolet radiation (UV) contributes to a variety of skin diseases including inflammation, degenerative aging, and cancer. Historically, humans have been exposed to UV radiation mainly through occupational exposure; recreational UV exposure, however ...
Bianchini, Daniela, Calvieri, Stefano, Cantisani, Carmen, Cantoresi, Franca, Faina, Valentina, Fazia, Gilda, Frascani, Federica, Paolino, Giovanni   +7 more
core   +3 more sources

Stability of 5-aminolevulinic acid in aqueous solution

European Journal of Pharmaceutical Sciences, 1999
The chemical stability of 5-aminolevulinic acid (ALA) was studied in aqueous solution as a function of concentration, pH, temperature and in the presence of ethylenediaminetetraacetic acid (EDTA). The degradation of ALA was followed by reversed-phase liquid chromatography using a pH where ALA is protonated (pKa1=3.90; pKa2=8.
B, Elfsson, I, Wallin, S, Eksborg, K, Rudaeus, A M, Ros, H, Ehrsson   +5 more
openaire   +2 more sources

Exogenous Glutathione and Nitric Oxide Improve Waterlogging Stress Tolerance in Maize

Plant-Environment Interactions, Volume 7, Issue 2, April 2026.
Exogenous glutathione (GSH) and nitric oxide (NO) enhance waterlogging tolerance in maize seedlings by reducing oxidative damage and improving growth. Combined GSH + NO treatment reduces H2O2 and malondialdehyde levels, enhances antioxidant defenses, protects photosynthetic pigments, and promotes biomass accumulation, thereby improving the ...
Prodipto Bishnu Angon, Md. Tahjib‐Ul‐Arif, Md. Sarwar Jahan, Md. Mahadi Hasan, Yoshiyuki Murata   +4 more
wiley   +1 more source

Topical photodynamic therapy using different porphyrin precursors leads to differences in vascular photosensitization and vascular damage in normal mouse skin [PDF]

, 2014
Different distributions of hexyl aminolevulinate (HAL), aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) in the superficial vasculature are not well studied but they are hypothesized to play an important role in topical photodynamic therapy ...
Bruijn, H.S. (Riette) de, Haas, E.R.M. (Ellen) de, Middelburg, T.A. (Tom), Neumann, H.A.M. (Martino), Ploeg-van den Heuvel, A. (Angélique) van der, Robinson, D.J. (Dominic), Vijlder, H.C. (Hanke) de   +6 more
core   +1 more source

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2541-2558, April 2026.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source