Results 121 to 130 of about 12,458,805 (285)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery

Diagnostics
(1) Background: Transsphenoidal pituitary surgery can be conducted via microscopic or endoscopic approaches, and there has been a growing preference for the latter in recent years.
Yun-Chen Chang, Yu-Ning Tsao, Chi-Cheng Chuang, Cheng-Yu Li, Ta-Jen Lee, Chia-Hsiang Fu, Kuo-Chen Wei, Chi-Che Huang   +7 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

5-FU-activated inflammasome pathway.

, 2014
Sa3 cells were incubated with 5 mg/mL of 5-FU for 0 to 24 h. (A), Western blot analysis of the expression of NLRP3 and the precursor of caspase-1 (pro-casp-1) in cell lysates. (B), Western blot analysis of cleaved caspase-1 (p20) in supernatants.
Hirohiko Okamura (658945), Kazuyoshi Kawazoe (658947), Daisuke Hinode (658948), Masami Yoshioka (658944), Satomi Moriyama (658946), Kaya Yoshida (658943), Daniel Grenier (522918)   +6 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Spectrophotometric analysis of 5-FU nano-particles.

, 2012
(A) Time kinetic effect of Aloe vera leaf extract mediated synthesis of 5-FU nano-particles employing UV Spectrophotometric analysis. The 5-FU solution was incubated with Aloe vera extract (5 ml of 10−3 M 5-FU and 5 ml Aloe vera extract; final volume of ...
Swaleha Zubair (179757), Mohammad Owais (179763), Arun Chauhan (179753), Asif Sherwani (179760)   +3 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Influence of acid antisecretory agents on the gastric corpus mucin accumulation in the 5-FU-induced gastric mucosal damage

, 2011
Fr-1 hexose values corresponding to mucin content are expressed as micrograms of hexose per rat and represent means ± SD. Abbreviations: 5-FU = 5-fluorouracil; Ome = omeprazole; Lan = lansoprazole; Laf = lafutidine.
Takafumi Ichikawa (93264), Nobuaki Shikama (93269), Yoichi Saegusa (93263), Tomohisa Iwai (93265), Yukinobu Goso (93266), Motoko Nakano (93268), Katsunori Saigenji (93270), Kazuhiko Ishihara (93271), Tomoaki Ikezawa (93267)   +8 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

CAC1 knockdown increased sensitivity of SW480/5-FU cells to 5-FU by influencing P-glycoprotein and MRP-1 expression.

, 2019
(A) SW480 and SW480/5-FU cells were transfected with shCAC1 and shCON for one week, and subjected to FACS analysis with Annexin V-FITC and propidium iodide staining.
Nanzheng Chen (7365800), Junke Fu (7365803), Qianqian Geng (1887229), Qi Gao (133189), Ying Kong (632793), Yunhua Wu (5745335), Xuejun Sun (46699)   +6 more
core   +1 more source