Results 121 to 130 of about 9,064,090 (287)
, 2011 Fr-1 hexose values corresponding to mucin content are expressed as micrograms of hexose per rat and represent means ± SD. Abbreviations: 5-FU = 5-fluorouracil; Ome = omeprazole; Lan = lansoprazole; Laf = lafutidine.
Takafumi Ichikawa (93264) +8 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
5-FU-activated inflammasome pathway.
, 2014 Sa3 cells were incubated with 5 mg/mL of 5-FU for 0 to 24 h. (A), Western blot analysis of the expression of NLRP3 and the precursor of caspase-1 (pro-casp-1) in cell lysates. (B), Western blot analysis of cleaved caspase-1 (p20) in supernatants.
Hirohiko Okamura (658945) +6 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 2019 (A) SW480 and SW480/5-FU cells were transfected with shCAC1 and shCON for one week, and subjected to FACS analysis with Annexin V-FITC and propidium iodide staining.
Nanzheng Chen (7365800) +6 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Spectrophotometric analysis of 5-FU nano-particles.
, 2012 (A) Time kinetic effect of Aloe vera leaf extract mediated synthesis of 5-FU nano-particles employing UV Spectrophotometric analysis. The 5-FU solution was incubated with Aloe vera extract (5 ml of 10−3 M 5-FU and 5 ml Aloe vera extract; final volume of ...
Swaleha Zubair (179757) +3 more
core +1 more source
Discover OncologyColorectal cancer (CRC) is a malignant digestive tumor associated with high mortality rate. Currently, 5-Fu therapy is a frequently used treatment approach for CRC.
Ya-nan Lu
doaj +1 more source
Diagnostics(1) Background: Transsphenoidal pituitary surgery can be conducted via microscopic or endoscopic approaches, and there has been a growing preference for the latter in recent years.
Yun-Chen Chang +7 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source