Results 11 to 20 of about 321,714 (246)

Clinical Characteristics of Alternaria Keratitis

open access: yesJournal of Ophthalmology, 2014
Purpose. Alternaria spp. are an uncommon cause of mycotic keratitis. Previous studies on Alternaria keratitis have generally been limited to case reports. We examined the clinical characteristics of Alternaria keratitis in this study. Methods.
Ching-Hsi Hsiao   +6 more
doaj   +1 more source

Anticancer Drug 5-Fluorouracil in Aqueous Solution by Differential Pulse Polarography: An Assessment of Optimum Conditions

open access: yesNano Biomedicine and Engineering, 2018
The potassium phosphate buffer as a supporting electrolyte of anticancer drug (5-fluorouracil (5-FU)) was the best among solutions of sodium phosphate buffer and Britton Robinson buffer in differential pulse polarography (DPP) at pH = 7.0 and T = 37 ...
Razzaq Abd Al-Zahra Ibrahim   +2 more
doaj   +1 more source

Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

open access: yesMolecular Cancer, 2006
Background Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival.
Kravik Katherine L   +3 more
doaj   +1 more source

Association of 5-FU Therapeutic Drug Monitoring to DPD Phenotype Assessment May Reduce 5-FU Under-Exposure

open access: yesPharmaceuticals, 2020
In order to limit 5-fluorouracil (5-FU) toxicity, some health agencies recommend evaluating dihydropyrimidine dehydrogenase (DPD) deficiency before any 5-FU treatment introduction.
Marine Dolat   +9 more
doaj   +1 more source

Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study

open access: yesThe Scientific World Journal, 2012
Objectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods.
Cheng-Hao Weng   +9 more
doaj   +1 more source

Obstetric and perinatal outcomes of pregnancy in patients with repeated implantation failure

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Despite the great advance of assisted reproductive technology (ART) in recent decades, many IVF patients failed to achieve a pregnancy even after multiple IVF-ET attempts.
Tzu Hsuan Chin   +9 more
doaj   +1 more source

The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2017
Objective: To investigate the effects of quercetin (Q) and rutin on 5-fluorouracil (5-FU)-induced hepatotoxicity. Methods: The control group was corn oil. The 5-FU group rats were corn oil and injected intraperitoneal 5-FU 50 mg/kg.
Volkan Gelen   +5 more
doaj   +1 more source

Fluorouracil (5-FU)-induced Cardiomyopathy [PDF]

open access: yesCureus, 2019
Fluorouracil (5-FU) is a pyrimidine analog widely used in oncology. It is mainly used in the treatment of solid tumors. It is also used along with radiotherapy because of its radiosensitizing properties. As with all chemotherapy drugs, 5-FU is associated with adverse effects. Cardiotoxicity is one of them.
Thalambedu, Nishanth, Khan, Yasir
openaire   +2 more sources

WDR76 regulates 5-fluorouracil sensitivity in colon cancer via HRAS

open access: yesDiscover Oncology, 2023
Background WD repeat domain 76 (WDR76) has been reported in multiple tumors, while without relation to chemotherapy resistance. 5-fluorouracil (5-FU) is widely adopted in treating colon cancer.
Yunlong Hu   +4 more
doaj   +1 more source

A comparative study of PALA, PALA plus 5-FU, and 5-FU in advanced breast cancer [PDF]

open access: yesCancer, 1985
Sixty-three patients with Stage IV breast carcinoma refractory to standard combination chemotherapy agents such as 5-fluorouracil (5-FU) were entered into a study to determine the efficacy of a multiple dose schedule of N-(phosphonacetyl)-L-aspartic acid (PALA) and whether the addition of PALA improves the therapeutic efficacy of 5-FU.
G B, Mann   +4 more
openaire   +2 more sources

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