Results 21 to 30 of about 12,458,805 (285)

Protracted infusional 5-fluorouracil (5-FU) with bolus mitomycin in 5-FU-resistant colorectal cancer

open access: yes, 2000
Background: MF (protracted infusion 5-fluorouracil (5-FU), 300 mg/m2/24 hours plus bolus mitomycin, 7 mg/m2 every 6 weeks, maximum 4 doses), was recently shown in a randomised trial to be superior to protracted 5-FU alone, as first-line chemotherapy for ...
Ride, E.   +4 more
core   +6 more sources

mDia formins are required for cell recovery in 5-FU-induced myeloid suppression.

open access: yes, 2023
(A) The numbers of HSPCs and committed progenitors from purified lineage-negative cells were analyzed and quantified by flow cytometer analysis by day 7 after 5-FU treatment.
Ermin Li (17712439)   +17 more
core   +1 more source

Table_1_Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway.doc

open access: yes, 2021
Oxidative stress induced by chemotherapeutic agents causes hepatotoxicity. 5-Fluorouracil (5-FU) has been found to have a variety of side effects, but its toxic effect on the liver and the mechanism are still unclear.
Yaping Wang (289641)   +10 more
core   +1 more source

Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study

open access: yesThe Scientific World Journal, 2012
Objectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods.
Cheng-Hao Weng   +9 more
doaj   +1 more source

Association of 5-FU Therapeutic Drug Monitoring to DPD Phenotype Assessment May Reduce 5-FU Under-Exposure

open access: yesPharmaceuticals, 2020
In order to limit 5-fluorouracil (5-FU) toxicity, some health agencies recommend evaluating dihydropyrimidine dehydrogenase (DPD) deficiency before any 5-FU treatment introduction.
Marine Dolat   +9 more
doaj   +1 more source

Obstetric and perinatal outcomes of pregnancy in patients with repeated implantation failure

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Despite the great advance of assisted reproductive technology (ART) in recent decades, many IVF patients failed to achieve a pregnancy even after multiple IVF-ET attempts.
Tzu Hsuan Chin   +9 more
doaj   +1 more source

The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2017
Objective: To investigate the effects of quercetin (Q) and rutin on 5-fluorouracil (5-FU)-induced hepatotoxicity. Methods: The control group was corn oil. The 5-FU group rats were corn oil and injected intraperitoneal 5-FU 50 mg/kg.
Volkan Gelen   +5 more
doaj   +1 more source

Fluorouracil (5-FU)-induced Cardiomyopathy [PDF]

open access: yesCureus, 2019
Fluorouracil (5-FU) is a pyrimidine analog widely used in oncology. It is mainly used in the treatment of solid tumors. It is also used along with radiotherapy because of its radiosensitizing properties. As with all chemotherapy drugs, 5-FU is associated with adverse effects. Cardiotoxicity is one of them.
Thalambedu, Nishanth, Khan, Yasir
openaire   +2 more sources

A comparative study of PALA, PALA plus 5-FU, and 5-FU in advanced breast cancer [PDF]

open access: yesCancer, 1985
Sixty-three patients with Stage IV breast carcinoma refractory to standard combination chemotherapy agents such as 5-fluorouracil (5-FU) were entered into a study to determine the efficacy of a multiple dose schedule of N-(phosphonacetyl)-L-aspartic acid (PALA) and whether the addition of PALA improves the therapeutic efficacy of 5-FU.
G B, Mann   +4 more
openaire   +2 more sources

Diet and the risk of inflammatory bowel disease: A retrospective cohort study in Taiwan

open access: yesJournal of the Formosan Medical Association
Background/purpose: The incidence of inflammatory bowel disease (IBD) rapidly increases in Asia, and western dietary pattern is suspected to be the major risk factor.
Ming Jung Meng   +6 more
doaj   +1 more source

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