Results 21 to 30 of about 52,894 (243)
Molecular Cancer, 2006 Background Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival.
Kravik Katherine L +3 more
doaj +1 more source
Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]
, 2001 Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
core +1 more source
The Scientific World Journal, 2012 Objectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods.
Cheng-Hao Weng +9 more
doaj +1 more source
Obstetric and perinatal outcomes of pregnancy in patients with repeated implantation failure
Taiwanese Journal of Obstetrics & Gynecology, 2019 Objective: Despite the great advance of assisted reproductive technology (ART) in recent decades, many IVF patients failed to achieve a pregnancy even after multiple IVF-ET attempts.
Tzu Hsuan Chin +9 more
doaj +1 more source
Fluorouracil (5-FU)-induced Cardiomyopathy [PDF]
Cureus, 2019 Fluorouracil (5-FU) is a pyrimidine analog widely used in oncology. It is mainly used in the treatment of solid tumors. It is also used along with radiotherapy because of its radiosensitizing properties. As with all chemotherapy drugs, 5-FU is associated with adverse effects. Cardiotoxicity is one of them.
Thalambedu, Nishanth, Khan, Yasir
openaire +2 more sources
RpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment [PDF]
, 2016 5-FU is a chemotherapy drug commonly used for the treatment of human cancers; however drug resistance represents a major challenge for its clinical application.
Botti, Gerardo +5 more
core +1 more source
WDR76 regulates 5-fluorouracil sensitivity in colon cancer via HRAS
Discover Oncology, 2023 Background WD repeat domain 76 (WDR76) has been reported in multiple tumors, while without relation to chemotherapy resistance. 5-fluorouracil (5-FU) is widely adopted in treating colon cancer.
Yunlong Hu +4 more
doaj +1 more source
The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats
Asian Pacific Journal of Tropical Biomedicine, 2017 Objective: To investigate the effects of quercetin (Q) and rutin on 5-fluorouracil (5-FU)-induced hepatotoxicity. Methods: The control group was corn oil. The 5-FU group rats were corn oil and injected intraperitoneal 5-FU 50 mg/kg.
Volkan Gelen +5 more
doaj +1 more source
A comparative study of PALA, PALA plus 5-FU, and 5-FU in advanced breast cancer [PDF]
Cancer, 1985 Sixty-three patients with Stage IV breast carcinoma refractory to standard combination chemotherapy agents such as 5-fluorouracil (5-FU) were entered into a study to determine the efficacy of a multiple dose schedule of N-(phosphonacetyl)-L-aspartic acid (PALA) and whether the addition of PALA improves the therapeutic efficacy of 5-FU.
G B, Mann +4 more
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Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents [PDF]
, 2019 This study reports the formation of 5-FU co-crystals with four different pharmacologically safe co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two fabrication schemes were followed i.e., solid-state grinding protocol, in
Abdelghani +53 more
core +2 more sources