Results 31 to 40 of about 16,556 (226)

Efeitos do exercício físico sobre os níveis séricos de serotonina e seu metabólito na fibromialgia: um estudo piloto randomizado

Revista Brasileira de Reumatologia, 2013
Avaliar os efeitos do treinamento aeróbico e do alongamento sobre os níveis séricos de serotonina (5-HT) e seu principal metabólito ácido 5-hidroxiindolacético (5-HIAA).
Valéria Valim, Jamil Natour, Yangming Xiao, Abraão Ferraz Alves Pereira, Beatriz Baptista da Cunha Lopes, Daniel Feldman Pollak, Eliana Zandonade, Irwin Jon Russell   +7 more
doaj   +1 more source

The Effect of Brain Serotonin on the Physiological Function

Psychiatry and Clinical Psychopharmacology, 2021
Serotonin (5-HT) is one of the newer neurotransmimmetrs to be recognized for physiological importance. 5-HT is involved in a variety of central nervous system function, such as control of the cardiovascular system, emotional behaviour, cerebral blood ...
Baria ÖZTAŞ
doaj  

5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice

Molecular Pain, 2011
Background The role of serotonin (5-hydroxytrptamine, 5-HT) in the modulation of pain has been widely studied. Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influence pain ...
Moessner Rainald, Gerlach Manfred, Lesch Klaus-Peter, Palm Florian, Chen Yong, Sommer Claudia   +5 more
doaj   +1 more source

Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit

Reproductive Biology and Endocrinology, 2023
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental functions, fetal development ...
Frantisek Staud, Xin Pan, Rona Karahoda, Xiaojing Dong, Petr Kastner, Hana Horackova, Veronika Vachalova, Udo R. Markert, Cilia Abad   +8 more
doaj   +1 more source

Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels

Frontiers in Surgery, 2022
IntroductionCarcinoid heart disease (CHD) is a consequence of neuroendocrine tumors releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart valves, causing fibrosis, and eventually right heart failure.
Husnain Abbas Shah, Vandana Sagar, Simon Hughes, Amardeep Khanna, Ivan Yim, Freya Lodge, Harjot Singh, Tessa Oelofse, Críostóir Ó'Súilleabháin, Hema Venkataraman, Shishir Shetty, Richard Steeds, Stephen Rooney, Tahir Shah   +13 more
doaj   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,, Buwalda, Bauke,, Jong, Jelly G. de,, Koolhaas, Jaap M.,, Ruiter, Anne J.H. de,, Vegt, Bea J. van der,   +5 more
core   +1 more source

Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid

Pharmaceuticals, 2022
The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ) and may contribute to cognitive ...
Korrapati V. Sathyasaikumar, Francesca M. Notarangelo, Deanna L. Kelly, Laura M. Rowland, Stephanie M. Hare, Shuo Chen, Chen Mo, Robert W. Buchanan, Robert Schwarcz   +8 more
doaj   +1 more source

Serotonin and motherhood: From molecules to mood [PDF]

, 2019
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming, Lonstein, Joseph S., Pawluski, Jodi L.   +2 more
core   +3 more sources

Alterations in Monoamine Metabolites in Alzheimer's Disease: A Comprehensive Meta‐Analysis of Cerebrospinal Fluid Levels [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) is a neurodegenerative disorder marked by cognitive decline and neuropsychiatric symptoms. The monoaminergic system, crucial for mood, cognition, and behavior regulation, is implicated in AD pathology. Alterations in monoamine metabolites like 3,4‐dihydroxyphenylacetic acid (DOPAC), 5‐hydroxyindoleacetic ...
Muneer M, Agarwa H, Gowda P, Azmi M, Yadav P, Ghosh V, Hassan M, Kaur A, Suresh V, Azzam A, Bardhan M.   +10 more
europepmc   +4 more sources

Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study. [PDF]

PLoS ONE, 2017
Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are the two most common causes of dementia. Both pathologies often coexist, and AD patients with concomitant neocortical LB pathology (referred to as the Lewy body variant of AD) generally show
Satoru Morimoto, Masaki Takao, Hiroyuki Hatsuta, Yasushi Nishina, Tadashi Komiya, Renpei Sengoku, Yuta Nakano, Akiko Uchino, Hiroyuki Sumikura, Yuko Saito, Kazutomi Kanemaru, Shigeo Murayama   +11 more
doaj   +1 more source