Results 101 to 110 of about 78,996,387 (176)

Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.

PLoS ONE, 2015
G protein-activated inwardly rectifying potassium (GIRK) channels in 5-HT neurons are assumed to be principal effectors of 5-hydroxytryptamine 1A (5-HT1A) autoreceptors, but their pharmacology, subunit composition and the role in regulation of 5-HT ...
Alberto Montalbano, Renato Corradetti, Boris Mlinar   +2 more
doaj   +1 more source

Receptores 5-HT1B/1D presentes no hipotálamo posterior medial e núcleo paraventricular envolvidos no controle serotonérgico da ingestão de alimento em pombos (Columba livia) [PDF]

, 2005
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em NeurociênciasNo presente estudo, investigou-se a presença de receptores serotonérgicos no hipotálamo posterior medial (PMH) e no ...
Poffo, Marine Josiane
core  

Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression

, 1993
Using in situ hybridization techniques, the expression of 5-HT1A receptor mRNA was measured within the hippocampal formation after bilateral adrenalectomy (ADX).
SJ Watson, DT Chalmers, SP Kwak, H Akil, A Mansour   +4 more
core   +1 more source

Activation of the serotonin-1A receptor promotes neural regeneration in the rat model of neonatal hypoxic–ischemic brain damage

Brain Research Bulletin
Perinatal hypoxic–ischemic brain damage (HIBD) is a leading cause of lifelong neurodevelopmental disability, and effective therapies remain limited. Activation of the postsynaptic serotonin-1A receptor (5-HT1A-R) has neuroprotective potential against ...
Xing Zhu, Mingrui Shi, Changyang Ma, Jie Yu, Juan Du, Mingyan Hei   +5 more
doaj   +1 more source

Effect of paroxetine and nefazodone on 5-HT1A receptor sensitivity.

, 2016
Animal experimental studies suggest that the therapeutic effect of selective serotonin re-uptake inhibitors (SSRIs) may involve neuroadaptive changes in pre- and post-synaptic serotonin1A (5-HT1A) receptors.

core   +1 more source

Fluoxetina y ciproheptadina- antagonismo en el receptor 5-HT1A

, 2019
La consideración de los efectos clínicos de los agonistas y antagonistas en cada receptor destaca la función clínica. La ciproheptadina bloquea los efectos secundarios sexuales de los SSRI al antagonizar los receptores 5-HT2A, pero puede provocar una ...
Mercedes Guaia Memita Guaia
core   +1 more source

Augmentation Therapy With Serotonin 5‐HT1A Receptor Partial Agonists on Cognitive Function in Depressive Disorders: A Systematic Review of Randomized Controlled Studies

Neuropsychopharmacology Reports
Objective The use of serotonin 5‐HT1A receptor partial agonists (5‐HT1A‐PAs) as an add‐on therapy has been associated with the enhancement of attention/processing speed in patients with schizophrenia. Also, 5‐HT1A receptors have been shown to play a role
Risa Yamada, Ayumu Wada, Andrew Stickley, Adrian Newman‐Tancredi, Tomiki Sumiyoshi   +4 more
doaj   +1 more source

Efeitos das injeções de agonistas e antagonistas gabaérgicos e agonistas serotonérgicos na concha do núcleo accumbens sobre comportamentos defensivos e ingestivos em ratos [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasA fim de estabelecer uma relacao funcional entre o controle dos comportamentos defensivos e ingestivos em ratos, esse ...
Lopes, Ana Paula Fraga
core  

Existence of Brain 5‑HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5‑HT1A Receptor Recognition

ACS Omega, 2017
Dasiel O. Borroto-Escuela, Xiang Li, Alexander O. Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fuxe   +13 more
doaj   +1 more source

Evidence for the existence of FGFR1–5-HT1A heteroreceptor complexes in the midbrain raphe 5-HT system

, 2015
The ascending midbrain 5-HT neurons known to contain 5-HT1A autoreceptors may be dysregulated in depression due to a reduced trophic support.
Ciruela, F, Fuxe, K,, Agnati, LF, Jiménez Beristain, A, Fuxe, K., Jimenez-Beristain, A, Belluardo, N, Borroto-Escuela, DO, BELLUARDO, Natale, MUDO', Giuseppa, Perez-Alea, M, Agnati, L, Tarakanov, AO, Borroto Escuela, D, Narvaez, M, Mudo, G, Tarakanov, A, Pérez Alea, M   +17 more
core   +1 more source