Results 121 to 130 of about 16,942 (208)

Sequencing 5-hydroxymethylcytosine [PDF]

Nature Methods, 2012
openaire   +1 more source

Tet proteins: on track towards DNA demethylation? [PDF]

, 2017
Dynamic DNA methylation is a prerequisite for many developmental processes and maintenance of cellular integrity. In mammals however, mechanisms of active DNA demethylation have for long been elusive.
Véron, Nathalie
core  

Functional analysis of 5-hydroxymethylcytosine

, 2014
Mammalian DNA methylathion is a chemical reaction catalyzed by DNA methyltransferases (DNMTs) and involves the addition of a methyl group from the methyl donor SAM to the carbon 5 position of cytosine (C) in a CpG dinucleotide. Specifically, DNA methylation is essential for normal development and is involved in numerous key mechanisms such as genomic ...
openaire   +1 more source

Genome-Wide 5-Hydroxymethylcytosine Profile [PDF]

, 2020
openaire   +1 more source

5-methylcytosine and 5-hydroxymethylcytosine are synergistic biomarkers for early detection of colorectal cancer. [PDF]

Commun Med (Lond)
Puddu F, Johansson A, Modat A, Scotcher J, Sethi R, Yu S, Harding N, Hill M, Lleshi E, Lumby C, Teyssandier J, Wilson M, Crawford R, Charlesworth T, Creed P, Balasubramanian S, Osborne RJ.   +16 more
europepmc   +1 more source

Editorial: Beyond CpG Methylation: New Modifications in Eukaryotic DNA

Frontiers in Cell and Developmental Biology, 2018
Reinhard Stöger, Alexey Ruzov
doaj   +1 more source

HM-DyadCap – capture and mapping of 5-hydroxymethylcytosine/5-methylcytosine CpG dyads in mammalian DNA [PDF]

Nucleic Acids Res
Engelhard L, Schiller D, Zambrano-Mila MS, Keliuotyte K, Buchmuller B, Tiwari S, Imig J, Simeone A, Schröter C, Becker S, Summerer D.   +10 more
europepmc   +2 more sources

Profiling of 5-hydroxymethylcytosine in blood reveals preferential enrichment at exon-intron junctions and predictive value for Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Antczak P, Brandt P, Radosavljević L, Svenningsson P, Rüegg J, Bečanović K.   +5 more
europepmc   +1 more source

5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease status in patients with osteosarcoma. [PDF]

NPJ Precis Oncol
Neczypor EW, Reisert H, Moore K, Zeldin E, Dubin RA, Battle L, He C, Hayashi M, Weiser DA, Applebaum MA.   +9 more
europepmc   +1 more source

5-Hydroxymethylcytosine: a key epigenetic mark in cancer and chemotherapy response. [PDF]

Epigenetics Chromatin
Kharat SS, Sharan SK.
europepmc   +1 more source