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Spectroscopic Quantification of 5-Hydroxymethylcytosine in Genomic DNA
Analytical Chemistry, 20145-Hydroxymethylcytosine (5hmC), a modified form of the DNA base cytosine, is an important epigenetic mark linked to regulation of gene expression in development, and tumorigenesis. We have developed a spectroscopic method for a global quantification of 5hmC in genomic DNA.
Tamar Shahal +5 more
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[Advances on the profiling of 5-hydroxymethylcytosine].
Yi chuan = Hereditas, 20165-hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. Accumulating studies have revealed the essential role of 5hmC in embryonic development, brain function and cancer research.
Ke, Fang +4 more
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5-Hydroxymethylcytosine-containing Klebsiella bacteriophage
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969N I, Anisymova +3 more
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Functional analysis of 5-hydroxymethylcytosine
2016Mammalian DNA methylathion is a chemical reaction catalyzed by DNA methyltransferases (DNMTs) and involves the addition of a methyl group from the methyl donor SAM to the carbon 5 position of cytosine (C) in a CpG dinucleotide. Specifically, DNA methylation is essential for normal development and is involved in numerous key mechanisms such as genomic ...
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Enzymatic Labeling of 5‐Hydroxymethylcytosine in DNA
Angewandte Chemie International Edition, 2011openaire +3 more sources
Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain
Angewandte Chemie - International Edition, 2010Martin Münzel +2 more
exaly
Synthesis of 5-Hydroxymethylcytosine
Journal of the American Chemical Society, 1955openaire +1 more source
5-hydroxymethylcytosine DNA glycosylase activity in mammalian tissue
Biochemical and Biophysical Research Communications, 1988George W Teebor
exaly