Results 31 to 40 of about 11,769,643 (158)

sj-docx-1-jop-10.1177_02698811211050543 – Supplemental material for A narrative synthesis of research with 5-MeO-DMT

, 2021
Supplemental material, sj-docx-1-jop-10.1177_02698811211050543 for A narrative synthesis of research with 5-MeO-DMT by Anna O Ermakova, Fiona Dunbar, James Rucker and Matthew W Johnson in Journal of ...
Anna O Ermakova (11591207), Fiona Dunbar (11591210), James Rucker (387336), Matthew W Johnson (5499914)   +3 more
core   +1 more source

2,5-Dimethylbufotenine and 2,5-dimethylbufotenidine: novel derivatives of natural tryptamines found in Bufo alvarius toads

Acta Crystallographica Section E: Crystallographic Communications, 2021
The solid-state structure of the bufotenine derivative bis(5-methoxy-2,N,N-trimethyltryptammonium) (5-MeO-2-Me-DMT) fumarate (systematic name: bis{[2-(5-methoxy-2-methyl-1H-indol-3-yl)ethyl]dimethylazanium} (2E)-but-2-enedioate), 2C14H21N2O+·C4H2O42 ...
Duyen N. K. Pham, Andrew R. Chadeayne, James A. Golen, David R. Manke   +3 more
doaj   +1 more source

A single inhalation of vapor from dried toad secretion containing 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting is related to sustained enhancement of satisfaction with life, mindfulness-related capacities, and a decrement of psychopathological symptoms [PDF]

Psychopharmacology, 2019
Natasha L Mason, Kim Kuypers, Malin Vedøy Uthaug   +2 more
exaly   +2 more sources

Speech markers of psychological change following a psychedelic 5-MeO-DMT retreat. [PDF]

J Psychopharmacol
Background: 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), a potent, short-acting psychedelic, induces profound shifts in cognition, affect, and self-awareness. Because language explicitly expresses these domains and voice implicitly conveys them, both may serve as potential ‘biomarkers’ of behavioural change.
Kuc J, McAlpine RG, Sellers A, Blackburne G, Lametti DR, Skipper JI.   +5 more
europepmc   +2 more sources

Innovative Psychedelic Therapies: Harnessing 5-MeO-DMT and DMT for Mental Health Treatment. [PDF]

ACS Med Chem Lett
Recent advancements in the therapeutic use of psychedelic compounds, particularly 5-MeO-DMT and DMT, have demonstrated significant potential in treating various mental health disorders. This Patent Highlight evaluates findings from multiple recent patents that explore novel applications of these compounds, including their use in severe psychiatric ...
Kargbo RB.
europepmc   +4 more sources

Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice

Acta Pharmaceutica Sinica B, 2016
We have shown recently that concurrent harmaline, a monoamine oxidase-A inhibitor (MAOI), potentiates serotonin (5-HT) receptor agonist 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT)-induced hyperthermia.
Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager, Stephan Schmidt, Ai-Ming Yu   +4 more
doaj   +1 more source

Examining the Potential Synergistic Effects Between Mindfulness Training and Psychedelic-Assisted Therapy

Frontiers in Psychiatry, 2021
Mindfulness-based interventions and psychedelic-assisted therapy have been experimentally utilised in recent years as alternative treatments for various psychopathologies with moderate to great success.
Maria Eleni Eleftheriou, Emily Thomas
doaj   +1 more source

A phase 1/2 trial to assess safety and efficacy of a vaporized 5-methoxy-N,N-dimethyltryptamine formulation (GH001) in patients with treatment-resistant depression

Frontiers in Psychiatry, 2023
BackgroundTreatment-resistant depression (TRD) is a substantial public health burden, but current treatments have limited effectiveness. The aim was to investigate the safety and potential antidepressant effects of the serotonergic psychedelic drug 5-MeO-
Johannes T. Reckweg, Cees J. van Leeuwen, Cécile Henquet, Therese van Amelsvoort, Eef L. Theunissen, Natasha L. Mason, Riccardo Paci, Theis H. Terwey, Johannes G. Ramaekers   +8 more
doaj   +1 more source

Phenomenology of 5-MeO-DMT and connection with aspects of mental health [PDF]

, 2023
Vzhledem k narůstajícím poznatkům o psychedelických sloučeninách v oblasti péče o duševní zdraví poskytnutých vědeckými výzkumy v posledních dekádách jsou následné účinky 5-MeO- DMT na aspekty duševního zdraví relativně neprobádány. Jeho jedinečné akutní
Živnůstka, Miroslav
core  

This is your brain on death: a comparative analysis of a near-death experience and subsequent 5-Methoxy-DMT experience

Frontiers in Psychology, 2023
IntroductionMuch research has focused on the modeling of the near-death experience (NDE) by classical and atypical psychedelics; however, to date, no study has reported on the relationship between the NDE and the experience induced by the highly potent ...
Pascal Michael, David Luke, David Luke, Oliver Robinson   +3 more
doaj   +1 more source