Results 131 to 140 of about 20,996,854 (289)
Journal of Virology, 2020 Over 130 modifications have been identified in cellular RNAs, which play critical roles in many cellular processes, from modulating RNA stability to altering translation efficiency.
Matthew J Eckwahl +6 more
semanticscholar +1 more source
, 2021 Background: DNA methylation is an important epigenetic modification, among which 5-methylcytosine methylation (5mC) is generally associated with tumorigenesis.
Xiaoning Li (581082) +10 more
core +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, EarlyView.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
DNA methylation editing by CRISPR-guided excision of 5-methylcytosine.
Journal of Molecular Biology, 2020 Tools for active targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epigenetic modification. DNA demethylation in mammals involve TET-mediated oxidation of 5-methylcytosine (5-meC),
I. Devesa-Guerra +7 more
semanticscholar +1 more source
Utilising Uracil DNA Glycosylase to detect the presence of 5-Methylcytosine
, 2014 DNA is regularly subjected to endogenous and exogenous reagents that cause mutations that can be detrimental to a cell if they are not repaired. One class of enzymes responsible for DNA repair is the family of DNA glycosylases and their role is to remove
Kimber, Scott T.
core
, 2022 Background: 5-methylcytosine has a profound impact on the development and progression of hepatocellular carcinoma. The aim of this study was to investigate the usefulness of 5-methylcytosine in determining the prognosis, tumor microenvironment, and ...
Haiying Wang (6869) +4 more
core +1 more source
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
Nature, 2010 TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of ...
M. Ko +19 more
semanticscholar +1 more source
The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections
International Journal of Molecular Sciences, 2020 Eukaryotic 5-methylcytosine RNA methyltransferases catalyze the transfer of a methyl group to the fifth carbon of a cytosine base in RNA sequences to produce 5-methylcytosine (m5C).
M. Wnuk +3 more
semanticscholar +1 more source
Molecular structure of cytosine (A) and 5-methylcytosine (B).
, 2014 Molecular structure of cytosine (A) and 5-methylcytosine (B).
Maria Luiza S. Mello (191454) +2 more
core +1 more source