Results 31 to 40 of about 9,556,040 (196)

6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral and White Matter Injury and Contributes to Functional Recovery

open access: yesFrontiers in Pharmacology, 2021
Hypoxic-ischemic encephalopathy (HIE) is one main cause of neonatal death and disability, causing substantial injury to white and gray matter, which can lead to severe neurobehavioral dysfunction, including intellectual disability and dyskinesia ...
Man Zhao   +7 more
doaj   +1 more source

Pivotal Role of Iron Homeostasis in the Induction of Mitochondrial Apoptosis by 6-Gingerol Through PTEN Regulated PD-L1 Expression in Embryonic Cancer Cells

open access: yesFrontiers in Oncology, 2021
Embryonic cancer stem cells (CSCs) can differentiate into any cancer type. Targeting CSCs with natural compounds is a promising approach as it suppresses cancer recurrence with fewer adverse effects.
Nipin Sp   +6 more
doaj   +1 more source

[6]‐Gingerol Inhibits Chikungunya Virus Infection by Suppressing Viral Replication [PDF]

open access: yesBioMed Research International, 2021
Chikungunya (CHIK) is a reemerging arboviral disease caused by chikungunya virus (CHIKV) infection. The disease is clinically hallmarked by prolonged debilitating joint pain. Currently, there is no specific antiviral medication nor commercial vaccine available for treatment of the disease, which makes the discovery or development of specific anti‐CHIKV
Rahma F. Hayati   +6 more
openaire   +2 more sources

Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell

open access: yesMolecules, 2017
Ginger has many bioactive compounds with pharmacological activities. However, few studies are known about these bioactive compounds activity in chemoresistant cells.
Chi-Ming Liu   +4 more
doaj   +1 more source

Pharmacological Aspects of 6-Gingerol: A Review

open access: yesAgricultural Science Digest - A Research Journal, 2021
Habitual consumption of raw fruits as well as vegetables can trim down the threat of many diseases. Ginger is consumed globally as a cuisine and herbal medicine. It is rich in pungent phenolic phytochemical substances together called gingerols. 6-Gingerol (1-[4’-hydroxy-3’-methoxyphenyl]-5-hydroxy-3- decanone) is the chief pharmacologically-active ...
openaire   +1 more source

[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice

open access: yesBMC Complementary and Alternative Medicine, 2017
Background [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is involved in insulin secretion and is perturbed in db/db Type-2 diabetic mice.
Mehdi Bin Samad   +9 more
doaj   +1 more source

Protective Effects of [6]-Gingerol Against Chemical Carcinogens: Mechanistic Insights

open access: yes, 2020
[6]-Gingerol from ginger has received considerable attention as a potential cancer therapeutic agent because of its chemopreventive and chemotherapeutic effects, as well as its safety. In the current study, we examined [6]-gingerol as a natural scavenger
Urban Bren, Veronika Furlan
core   +1 more source

Therapeutic Potential of 6-Gingerol in Prevention of Colon Cancer Induced by Azoxymethane through the Modulation of Antioxidant Potential and Inflammation

open access: yesCurrent Issues in Molecular Biology, 2022
A polyphenolic component of ginger, 6-gingerol, is widely reported to possess antioxidant, anti-inflammatory and anticancer activities. In the current study, it was aimed to investigate the anticancer effects of 6-gingerol (6-Gin) on azoxymethane (AOM ...
Abdulaziz A. Aloliqi
doaj   +1 more source

Reduced HIF-1α Stability Induced by 6-Gingerol Inhibits Lung Cancer Growth through the Induction of Cell Death

open access: yesMolecules, 2022
Lung cancer (LC) is the leading global cause of cancer-related death, and metastasis is a great challenge in LC therapy. Additionally, solid cancer, including lung, prostate, and colon cancer, are characterized by hypoxia.
Min Jeong Kim   +7 more
doaj   +1 more source

[6]-Gingerol Induces Cell Cycle Arrest and Cell Death of Mutant p53-expressing Pancreatic Cancer Cells [PDF]

open access: yes, 2006
[6]-Gingerol, a major phenolic compound derived from ginger, has anti-bacterial, anti-inflammatory and anti-tumor activities. While several molecular mechanisms have been described to underlie its effects on cells in vitro and in vivo, the underlying ...
박승우, 방승민, 송시영
core   +1 more source

Home - About - Disclaimer - Privacy