Results 61 to 70 of about 9,551,377 (187)

Molecular mechanism inhibiting human hepatocarcinoma cell invasion by 6-shogaol and 6-gingerol

open access: yes, 2014
Scope: We previously demonstrated that 6-shogaol and 6-gingerol, two active compounds in ginger (Zingiber officinale), possess antiinvasive activity against highlymetastatic hepatoma cells.
Chou, Chai-Ping   +3 more
core   +1 more source

Therapeutic effect of 6-shogaol on acetaminophen-induced hepatotoxicity in mice: an experimental study.

open access: yesEuropean review for medical and pharmacological sciences, 2022
Acetaminophen (APAP) is one of the most commonly used analgesics and antipyretics. It causes serious liver damage when taken in large quantities by adults or children. Also, 6-shogaol is an active compound obtained from ginger with anti-inflammatory and antioxidant properties.
GÜNAY, NURULLAH   +3 more
openaire   +5 more sources

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

open access: yesPhytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren   +10 more
wiley   +1 more source

Induction of autophagy by 6-shogaol.

open access: yes, 2015
MCF-7 cells were treated with 6-shogaol (15 μM) or chloroquine (50 μM) for 48 hours. Top panel: Bright field image (20X) of control and treated cells. Arrow heads indicates cytoplasmic vacuolization.
Anasuya Ray (793851)   +2 more
core   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

open access: yesPhytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li   +4 more
wiley   +1 more source

Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol.

open access: yes, 2016
All four compounds possess a vanilloid moiety. Capsaicin and RTX have strong potency, while [6]-shogaol and [6]-gingerol have moderate potency against TRPV1.
Katsuya Ohbuchi (559460)   +5 more
core   +1 more source

Inhibitory Effect of 6-shogaol on Fructose-Induced Protein Glycation and Oxidation in Vitro [PDF]

open access: yes, 2017
Advanced glycation end product (AGEs), the final products derived from the non enzymatic modification of proteins by reducing sugars, plays an important role in the development of diabetic complications.
Pengnet, Sirinat, Malakul, Wachirawadee
core   +1 more source

The possibility of using shogaol for treatment of ulcerative colitis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective(s): This study aimed to investigate the effect of Shogaol on dextran sodium sulfate (DSS)- induced ulcerative colitis (UC) in mice compared to an immune-suppressant chemotherapeutic medicine, known as 6-thioguanine (6-TG). Materials and Methods:
Snur Hassan, Ali Hassan
doaj   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi   +5 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

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