Results 71 to 80 of about 9,551,377 (187)

Oral Ulcerations and Phytotherapy: Potential Role of Helichrysum Essential Oil—A Literature Review

Oral Diseases, EarlyView.
ABSTRACT Background Recurrent aphthous stomatitis (RAS) is a common yet therapeutically challenging chronic inflammatory disease of the oral mucosa, characterized by recurrent, painful ulcerations that substantially affect patients' quality of life. Objective This review summarizes current evidence on phytotherapy in RAS, with particular focus on the ...
Ruzica Ivkovic, Reka Antic, Avisek Majumder, Suravi Majumder, Dragana Stanisic   +4 more
wiley   +1 more source

Conversion of 6-gingerol to 6-shogaol in ginger (Zingiber officinale) pulp and peel during subcritical water extraction

, 2020
Subcritical water extraction is an eco-friendly method for the extraction of less polar compounds without the use of organic solvents. This study determined the extraction conditions that maximize the contents of 6-gingerol and 6-shogaol obtained from ...
고민정, 정명수
core   +1 more source

Targeted Metabolomics Reveals Tissue‐Specific Accumulation and Translocation of Bioactive Compounds in Ginger During Growth

Food Frontiers, Volume 7, Issue 5, September 2026.
Targeted UHPLC–MS/MS methods were established to quantify 32 bioactive compounds in ginger leaves, stems, and rhizomes during growth. Distinct tissue‐specific accumulation and translocation patterns were observed, and aminoacyl‐tRNA biosynthesis was identified as the most active pathway in ginger development.
Yinfeng Zhao, Qin Wang, Jiguang Zhang, Xiuhua Liu, Yixuan Jiang, Qingzhi Li, Chunhua Shang, Min Lin, Rui Weng, Jing Qiu, Yongzhong Qian   +10 more
wiley   +1 more source

Beneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice

Diabetology & Metabolic Syndrome, 2019
Background Diabetes is characterized by hyperglycemia due to impaired insulin secretion and aberrant glucagon secretion resulting from changes in pancreatic islet cell function and/or mass.
Jun-Koo Yi, Zae-Young Ryoo, Jae-Jung Ha, Dong-Yep Oh, Myoung-Ok Kim, Sung-Hyun Kim   +5 more
doaj   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

[6]-Shogaol Induces Apoptosis of Murine Bladder Cancer Cells

Cellular Physiology and Biochemistry
Background/Aims: Bladder cancer is considered one of the most aggressive neoplasms due to its recurrence and progression profile, and even with the improvement in diagnosis and treatment methods, the mortality rate has not shown a declining trend in recent decades.
Diana Gabriela, Nina Nina, Thaiane Alcarde, Robeldo, Almada da, Silva, Vitória Shiévila, Dos Santos Gonçalves, Ricardo Carneiro, Borra, Fernanda de Freitas, Anibal   +5 more
openaire   +2 more sources

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting

MedComm, Volume 7, Issue 9, September 2026.
This review illustrates heat shock proteins (HSPs) as central regulators of cancer metabolic reprogramming. By stabilizing key metabolic enzymes and coordinating glycolysis, oxidative phosphorylation, redox homeostasis, and stress adaptation, HSPs support tumor growth, metastasis, and therapeutic resistance. Targeting HSP networks may therefore provide
Sheng Ma, Chen‐Qian Liu, Si‐Yang Ma, Shao‐Gang Wang, Qi‐Dong Xia, Meng‐Yao Xu   +5 more
wiley   +1 more source

Temperature effects on diffusion coefficient for 6-gingerol and 6-shogaol in subcritical water extraction [PDF]

, 2014
6-gingerol and 6-shogaol are the main constituents as anti-inflammatory or bioactive compounds from zingiber officinale Roscoe. These bioactive compounds have been proven for inflammatory disease, antioxidatives and anticancer.
Iwai, Yoshio, Morad, Nor Ilia Anisa, Morad, Noor Azian, Aris, Nor Ilia Anisa, Md. Sarip, Mohd. Sharizan, Sarip, Mohd. Sharizan, Aris, Noor Azian   +6 more
core   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source

Radioiodinated Ginger Compounds (6-gingerol and 6-shogaol) and Incorporation Assays on Breast Cancer Cells

, 2020
Background: 6-Gingerol (6G) and 6-Shogaol (6S) are the main active components of ginger. 6-Gingerol is known for its anti-metastatic and anti-invasive pharmacological activities on cancer cells, besides, 6-Shogaol also inhibits breast cancer cell ...
Kilcar, Ayfer Yurt, Karatay, Kadriye B.
core   +1 more source