Results 141 to 150 of about 920 (179)

Tire Rubber Antioxidant 6PPD and 6PPD-quinone Disrupt the Energy Supply and Lipid Metabolism of Earthworms

Environmental Science & Technology
With the increase in traffic due to urbanization, tire wear particles (TWPs) derived compounds persistently accumulate in the soil environment. This study addresses critical knowledge gaps regarding the ecotoxicological effects of TWP-derived contaminants, N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its precursor, 6PPD-quinone (6PPD-Q)
Yanyu Bao, Weitao Liu, Baoshan Xing
exaly   +3 more sources

Environmental concentrations of 6PPD and 6PPD-quinone induce hepatic lipid metabolism disorders in male black-spotted frogs

Journal of Hazardous Materials
Aquatic environments are generally contaminated with N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPD-Q). Recently, 6PPD-Q was found lethally toxic to some specific species, especially salmonid silverfish.
Liping Lu, Zhiquan Liu, Wenhui Sun
exaly   +3 more sources

6PPD and 6PPD Quinone Induce Endometrial Cell Dysfunction via Activating ERα and GPER at Human-Relevant Levels

Environmental Science & Technology
The widespread environmental prevalence of tire-derived N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and 6PPD-quinone (6PPD-Q) has provoked public concern about their health risks. This study aimed to investigate the potential of 6PPD and 6PPD-Q to induce endometrial cell dysfunction through nuclear estrogen receptor (ER) and G-protein ...
Linying Cao
exaly   +3 more sources

First Insights into 6ppd Quinone Formation from 6ppd Photodegradation in Water Environment

Journal of Hazardous Materials, 2023
p-Phenylenediamines (PPDs), an important type of rubber antioxidants, have received little study on their environmental fate, particularly for their vital photodegradation process in water environment. Accordingly, N-(1,3-dimethylbutyl)-N'-phenyl-1,4-phenylenediamine (6PPD), as a representative of PPDs, was investigated experimentally and theoretically
Chenguang, Li, Yanlei, Zhang, Shiqi, Yin, Qin, Wang, Yuanyuan, Li, Qiang, Liu, Liuqingqing, Liu, Xianxiang, Luo, Lingyun, Chen, Hao, Zheng, Fengmin, Li   +10 more
openaire   +2 more sources

A Transcriptomic View of 6PPD and 6PPD-Q in Pimephales promelas

2022
Presentation to the Society of Environmental Toxicology and Chemistry (SETAC) North America 43rd Annual Meeting November 2022 Search for CCTE records in EPA’s Science Inventory by typing in the title at this link. https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID ...
Bush, Kendra, Hazemi, Monique, Hoang, John, Le, MIchelle, Blackwell, Brett, Flynn, Kevin, Stacy, Emma, Villeneuve, Dan   +7 more
openaire   +1 more source

Policy recommendations for tire additive 6PPD and its derivative 6PPD-Q

Around 3.1 billion tires are produced around the world annually1. The antioxidant additive, 6PPD (i.e., N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine) is widely employed in passenger and commercial vehicle tires at 0.4-2% by mass to impede tire ...
King, Ashley E.
openaire   +2 more sources

Oral Exposure to Tire Rubber-Derived Contaminant 6ppd and 6ppd-Quinone Induced Hepatotoxicity in Mice

SSRN Electronic Journal, 2022
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is a widely used additive for protecting various rubber products, and its product of oxidation N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPDQ) has attracted extensive attention in aquatic toxicity.
Liya, Fang, Chanlin, Fang, Shanshan, Di, Yundong, Yu, Caihong, Wang, Xinquan, Wang, Yuanxiang, Jin   +6 more
openaire   +2 more sources

Enhanced photodegradation of 6PPD and formation of 6PPD-quinone in ice

Water Research
The widespread occurrence of 6PPD-quinone (6PPD-Q), a highly toxic transformation product of the tire-derived antioxidant 6PPD, poses serious threat to salmon fisheries. Here, we provide the first quantitative evaluation of 6PPD phototransformation in ice under UV irradiation, a condition directly relevant to salmon habitats.
Jingqi Ruan, Teng Zhang, Peizeng Yang, Xinping Yang, Bin Gao, Junhe Lu, Deyang Kong   +6 more
openaire   +2 more sources

Comparative growth inhibition of 6PPD and 6PPD-Q on microalgae Selenastrum capricornutum, with insights into 6PPD-induced phototoxicity and oxidative stress

Science of The Total Environment
Widespread environmental detection of tire additive N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its toxic metabolite 6PPD-Q has raised great concerns for their potential impact on aquatic biota. This study investigated the effects of 6PPD and 6PPD-Q on the model green microalgae (Selenastrum capricornutum). Results showed that 6PPD at
Xiaopeng, Yan, Claude, Kiki, Zijie, Xu, Habasi Patrick, Manzi, Azhar, Rashid, Tianyuan, Chen, Qian, Sun   +6 more
openaire   +2 more sources

Ecotoxicity of 6PPD and 6PPD-Q in aquatic ecosystems: Mechanisms, influencing factors, and mitigation strategies

Journal of Hazardous Materials
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPD-Q) are widely present in the environment due to their extensive use in rubber products, especially tires. Once released, 6PPD undergoes transformation to 6PPD-Q, which has been detected in air, dust, sediments, surface waters, and wastewater ...
Xuan Zhang, Ruiying Shi, Xinwei Shi, Junjie Du, Yanhua He, Weitao Liu   +5 more
openaire   +2 more sources