Results 151 to 160 of about 920 (179)

Environmental fate, toxicity, and mitigation of 6PPD and 6PPD-Quinone: Current understanding and future directions

Environmental Pollution
N'-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a widely used antioxidant in the rubber industry, has garnered global attention due to the high toxicity and ecological-health risks posed by its environmental oxidation product, 6PPD-quinone (6PPD-Q).
Jia Yi, Jing Ruan, Haiyang Yu, Baihui Wu, Jing Zhao, Hanbing Wang, Rongbing Chen, Qinsi Yang, Jiangfei Chen, Da Sun   +9 more
openaire   +2 more sources

Exploring a green-approach for 6PPD and 6PPD-Q removal: Riverine plants in natural wetlands

Journal of Hazardous Materials
The tire-derived antioxidant 6PPD and its highly toxic transformation product (TP) 6PPD-Q represent an emerging threat to aquatic ecosystems. For example, 6PPD-Q is identified as the cause of acute mortality in coho salmon. This study investigates the phytoremediation potential of riverine plants in natural wetlands (e.g. Typha minima (T.
Yu Lei, Xiaopeng Yan, Shengwen Zhao, Qian Zhang, Luo Liu, Qian Sun   +5 more
openaire   +2 more sources

6PPD, Not 6PPD-Quinone, Induced Serious Zebrafish Eye Damage by Disrupting the Thyroid Signaling Pathway

Environmental Science & Technology
N-(1,3-Dimethylbutyl)-N'-phenyl-1,4-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ) showed different acute toxicities and bioaccumulation potencies in fish. In this study, we compared the thyroid disrupting effects of 6PPD and 6PPDQ through in vitro, in silico, and in vivo assays.
Jing Chang, Leisen Zhang, Juan Zhao, Zhaoguang Zhang, Zijian Wang, Huili Wang, Bin Wan   +6 more
openaire   +2 more sources

Occurrence, Transformation, and Toxicity of Tire-Derived Chemicals 6PPD and 6PPD-q in the Environment

Environmental Science & Technology
6PPD (N1-(4-methylpentan-2-yl)-N4-phenylbenzene-1,4-diamine), a widely used rubber antioxidant in tire manufacturing, has garnered increasing global attention, following the discovery that its ozone-oxidation product, 6PPD-q, is the primary toxicant responsible for urban runoff mortality syndrome (URMS) in salmon.
Shuang Wang, Shuhan Xu, Junhe Lu, Yongshan Wan, Zhenyu Kang, Hao Chen, Shahidul Islam, Bin Gao   +7 more
openaire   +2 more sources

Insights into the impact of 6PPD-Q and 6PPD on nitrogen metabolism and microbial community in the anammox system

Environmental Research
N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is an antioxidant commonly used in tire manufacturing, and its release into the environment has significantly increased due to rapid urbanization. When subjected to ozonation, 6PPD converts into the harmful pollutant 6PPD quinone (6PPDQ). These substances enter wastewater treatment plants (WWTPs)
Xingyao, Ye, Xiaojun, Niu, Ling, Li, Mengyu, Lv, Dongqing, Zhang, Deye, Chen, Yu, Line, Zhiquan, Yang   +7 more
openaire   +2 more sources

Developing water quality criteria and assessing ecological risks for 6PPD and 6PPD-Q in freshwater ecosystems

Environmental Pollution
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its derivative N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q), originating from tire wear particles (TWPs), are emerging contaminants (ECs) of growing concern. This study focused on the development of water quality criteria (WQC) for 6PPD and 6PPD-Q in freshwater ...
Hao Zhang, Li Li, Jinlin Jiang, Ziyan Zhou, Qiang Chen, Tao Long   +5 more
openaire   +2 more sources

Tire rubber derivative 6PPD and 6PPD-Q induce lipid accumulation in hepatocytes through ERRγ pathway

Journal of Environmental Sciences
N-phenyl-N'-(1,3-dimethylbutyl)-p-phenylenediamine (6PPD) is a tire rubber antioxidant that can be oxidized to form derivative 6PPD-quinone (6PPD-Q). 6PPD and 6PPD-Q have been detected in human urine with concentrations reaching nanomolar levels. However, their human adverse effects and toxic mechanisms are not explicit.
Shike Zhang, Xinyi Su, Jiada Zhang, Tingting He, Lei Tang, Zepei Zhao, Linying Cao   +6 more
openaire   +2 more sources

6PPD and 6PPD-Q Inhibit Macrophyte Photosynthesis by Targeting Photosynthetic Antenna: Multiomics and Computational Modeling Insights

Environmental Science & Technology
Emerging evidence indicates that N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its derivative 6PPD-quinone (6PPD-Q) exert photosynthetic toxicity on aquatic macrophytes. However, their precise inhibitory mechanisms and toxic targets within the photosynthetic pathways remain poorly understood.
Xiang Li, Weitao Liu, Ruiying Shi, Yichen Ge, Qi Wang, Chuan Yin, Jinzheng Liu, Xinwei Shi, Fan Mo, Cuihong Chen, Jing An   +10 more
openaire   +2 more sources

Derivation of acute aquatic life screening values for 6PPD and 6PPD-quinone in freshwaters by USEPA Office of Water

Environmental Toxicology and Chemistry
Abstract In June 2024, the U.S. Environmental Protection Agency (USEPA) Office of Water published aquatic life screening values for acute freshwater exposures to two widely distributed rubber-tire compounds, N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylene diamine (6PPD) and N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylene diamine quinone (6PPD-
Amanda Jarvis, Kristen Prossner, Brian Schnitker, Kathryn Gallagher   +3 more
openaire   +2 more sources

Oral exposure to tire rubber-derived contaminant 6PPD and 6PPD-quinone induces intestinal toxicity in mice

Toxicology
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is a commonly used rubber protectant that continuously enters the environment via groundwater. Its oxidation product, N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPDQ), has garnered significant concern due to its reported toxicity in animals.
Liya, Fang, Jinhua, Xu, Chanlin, Fang, Yuanxiang, Jin   +3 more
openaire   +2 more sources