Tumor necrosis factor‐α and the formation of reactive oxygen intermediates are central mediators of apoptosis. Recent data indicated a role of neopterin and 7,8‐dihydroneopterin in oxygen radical mediated processes. We have therefore investigated the effect of neopterin‐derivatives on TNFα induced apoptosis of the monocyte‐like cell line U937.
Baier-Bitterlich, Gabriele +8 more
openaire +2 more sources
Muscle damage caused through impacts in rugby union is known to increase oxidative stress and inflammation. Pterins have been used clinically as markers of oxidative stress, inflammation, and neurotransmitter synthesis. This study investigates the release of myoglobin from muscle tissue due to force‐related impacts and how it is related to the ...
A, Lindsay +6 more
openaire +4 more sources
Background Folate is essential for Deoxyribonucleic acid (DNA) synthesis, methylation and repair, with deficiencies linked to neural tube defects, Alzheimer’s, and cancer.
Rahma Ali Hassan Abubakr +4 more
doaj +1 more source
Neopterin/7,8-dihydroneopterin is elevated in Duchenne muscular dystrophy patients and protects mdx skeletal muscle function. [PDF]
Lindsay A +4 more
europepmc +1 more source
Metabolic and Gut Microbiome Responses to Paraquat Exposure in <i>Apis mellifera</i> Under Laboratory Conditions. [PDF]
Mills N +11 more
europepmc +1 more source
Emerging roles of pterins as signaling molecules in bacteria. [PDF]
Rucker P, Augusta L, Fuqua C, Allen KD.
europepmc +1 more source
Identification of a Novel Dihydroneopterin Aldolase as a Key Enzyme for Patulin Biodegradation in <i>Lactiplantibacillus plantarum</i> 6076. [PDF]
Shi Y +5 more
europepmc +1 more source
Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design. [PDF]
Shaw GX +5 more
europepmc +1 more source
The Occurrence of Folate Biosynthesis Genes in Lactic Acid Bacteria from Different Sources. [PDF]
Mahara FA +3 more
europepmc +1 more source
The antioxidants neopterin/7,8‐dihydroneopterin: Novel biomarker and muscle protectant in Duchenne muscular dystrophy [PDF]
openaire +3 more sources

