Results 91 to 100 of about 320 (132)
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Ozonolysis of 7-dehydrocholesterol acetate peroxide
Tetrahedron Letters, 1979Abstract Secodione 3 and hemiacetal 4 from ozonolysis of peroxide 2 were obtained. A tentative mechanism of their formation is proposed.
J. Gumułka +2 more
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Occurrence of 7-dehydrocholesterol in the uropygial gland of domestic fowls
Acta Histochemica, 1978Histochemical studies on the uropygial gland of domestic fowls have shown the presence of sterols (among which cholesterol and its esters) in the lipidic fraction of the gland secret. beta-Glucuronidase activity beside A5 3beta- and 17beta-hydroxysteroid dehydrogenase activities suggests that uropygial gland might be involved in sterols metabolism.
UVA, BIANCA MARIA +5 more
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Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells
Free Radical Biology and Medicine, 2014Ultraviolet radiation is the main cause of skin cancers, and melanoma is the most serious form of tumor. There is no therapy for advanced-stage melanoma and its metastasis because of their high resistance to various anticancer therapies. Human skin is an important metabolic organ in which occurs photoinduced synthesis of vitamin D3 from 7 ...
GELZO, MONICA +7 more
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Inhibition of the conversion of 7-dehydrocholesterol to cholesterol by AY-9944
Biochemical and Biophysical Research Communications, 1964Abstract We have reported recently on the effect of trans -1,4- bis (2-chlorobenzylaminomethyl)cyclohexane dihydrochloride (AY-9944) (Humber, 1963) on hepatic cholesterogenesis in rat liver homogenates (Dvornik et al. , 1963) . In vitro , AY-9944 (a) prevented the incorporation of 2-C 14 -mevalonate into cholesterol but not into
M, Kraml, J F, Bagli, D, Dvornik
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Probing the Biexponential Dynamics of Ring-Opening in 7-Dehydrocholesterol
The Journal of Physical Chemistry A, 2016Our prior discovery of a novel biexponential photochemical ring-opening in 7-dehydrocholesterol (DHC) to previtamin D3 [ Tang J. Chem. Phys. 2011 , 134 , 104503 ] is further explored with ultrafast transient absorption spectroscopy, and the results are compared with recently reported high-level theoretical calculations.
Broc D, Smith +2 more
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The site of 7-dehydrocholesterol ultraviolet photolysis in domestic fowls
Acta Histochemica, 1983The site of the photolytic reaction leading to Vitamin D3 in fowls integument has been investigated by histochemical and biochemical analysis. The Vitamin D3 precursor, 7-dehydrocholesterol, is synthetized and stored mainly in the uropygial gland and in the same localization several amount of Vitamin D3 may be biochemically detected.
B, Uva, A, Mandich, M, Vallarino
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Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol
Biochemical and Biophysical Research Communications, 1981Abstract An inhibition of human fibroblast sphingomyelinase by cholesterol and 7-dehydrocholesterol is shown. This effect is obtained for cholesterol and 7-dehydrocholesterol/sphingomyelin molar ratios above 0.1. Diffusion measurements performed on mixed liposomes demonstrated for cholesterol/sphingomyelin and 7-dehydrocholesterol/sphingomyelin molar
J C, Maziere +5 more
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7-Dehydrocholesterol: A sterol shield against an iron sword
Molecular CellLi et al. and Freitas et al. recently identified 7-dehydrocholesterol (7-DHC), a sterol produced through the cholesterol biosynthetic pathway, as a lipid-soluble antioxidant that protects cells from ferroptosis, a cell death pathway triggered by iron-catalyzed phospholipid peroxidation.1,2.
Shaojie Cui, Jin Ye
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A new synthesis of 7-dehydrocholesterols
The Journal of Organic Chemistry, 1981Pat N. Confalone +2 more
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