Results 81 to 90 of about 13,198 (194)

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure [PDF]

, 2018
K
Balogh, István, Garbett, Krassimira A., Genaro-Mattos, Thiago C., Koczok, Katalin, Korade, Zeljka, Liu, Wei, Mirnics, Károly, Porter, Ned A., Tallman, Keri A.   +8 more
core   +1 more source

A pilot study of maternal vitamin D status and its association with breast milk and infant gut metabolites

Physiological Reports, Volume 14, Issue 5, March 2026.
Vitamin D status in our pilot study was associated with higher levels of certain amino acids and hexanoic acid in breast milk and metabolites in infant stool samples. Abstract Human milk contains multiple bioactive components, many of which are influenced by the mother's nutritional status.
Alyssa S. Gutierrez, Katherine E. Chetta, Santosh Thapa, Sigmund J. Haidacher, Kathleen M. Hoch, John E. Baatz, Anthony M. Haag, Numan Oezguen, Thomas D. Horvath, Carol L. Wagner, Melinda A. Engevik   +10 more
wiley   +1 more source

Osteomalacia Following Iron Infusion Therapy in a Patient With Rendu‐Osler‐Weber Syndrome: F‐18‐FDG PET/CT Discrimination of a Stress Fracture in the Setting of a Musculoskeletal Tumor Mimic

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT This case report highlights a rare occurrence of osteomalacia induced by hypophosphatemia secondary to ferric carboxymaltose (FCM) therapy in a patient with hereditary hemorrhagic telangiectasia (HHT, or Rendu‐Osler‐Weber syndrome). A 21‐year‐old man presented with left tibial pain without prior trauma, accompanied by severe hypophosphatemia ...
Ioannis S. Vasios, Pipitsa N. Valsamaki, Konstantinos Tilkeridis, Savvas Deftereos, Efthymios Iliopoulos   +4 more
wiley   +1 more source

The effect of vernal solar UV radiation on serum 25-hydroxyvitamin D concentration depends on the baseline level : observations from a high latitude in Finland [PDF]

, 2017
Humans obtain vitamin D from conversion of 7-dehydrocholesterol in the skin by ultraviolet B (UVB) radiation or from dietary sources. As the radiation level is insufficient in winter, vitamin D deficiency is common at higher latitudes.
Ala-Houhala, Meri, Hannula, Henna-Reetta, Karppinen, Toni, Kautiainen, Hannu, Lakkala, Kaisa, Reunala, Timo, Snellman, Erna, Turunen, Esa, Viljakainen, Heli, Ylianttila, Lasse   +9 more
core   +1 more source

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

A new metabolic path in type 3 rickets

The FEBS Journal, Volume 293, Issue 3, Page 656-659, February 2026.
Rickets, a bone disorder, was historically categorised into either nutritional (vitamin D deficiency) or genetic forms involving loss‐of‐function mutations in mineral metabolism. Recently, a new mechanism, type 3 rickets, was discovered to be caused by a gain‐of‐function mutation in CYP3A4 (Ile301Thr).
Toshiya Senda, Yoshihisa Hirota
wiley   +1 more source

Neutral sterols of rat epididymis: high concentrations of dehydrocholesterols in rat caput epididymidis

Journal of Lipid Research, 2001
Phospholipids and sterols are known to have multiple functions in reproductive tissue of mammals. High concentrations of the cholesterol precursor desmosterol have been described in testis, epididymis, and spermatozoa of various species.
Bernhard Lindenthal, Tayseer A. Aldaghlas, Joanne K. Kelleher, Stephan M. Henkel, René Tolba, Gerhard Haidl, Klaus von Bergmann   +6 more
doaj   +1 more source

The effect of high-dose vitamin D supplementation on muscular function and quality of life in postmenopausal women—A randomized controlled trial [PDF]

, 2017
Objective: Observational studies have suggested positive associations between serum 25-hydroxyvitamin D (25(OH)D) levels and muscular strength, balance and quality of life.
Cashman, Kevin D., Emaus, Nina, Grimnes, Guri, Jorde, Rolf   +3 more
core   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, Volume 108, Issue 2, Page 676-693, February 2026.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source