Results 51 to 60 of about 1,092 (179)

First evaluation of glucose-6-phosphate dehydrogenase (G6PD) deficiency in vivax malaria endemic regions in the Republic of Korea. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect and affects more than 400 million people worldwide.
Youn-Kyoung Goo   +6 more
doaj   +1 more source

Anti-pneumoscystis carinni activitiy of primaquine imidazolidin-4-ones [PDF]

open access: yes, 2006
Pneumocystis pneumonia (PCP) is one of the most frequent causes of mortality among HIV-infected patients. Primaquine (PQ) is an antimalarial 8-aminoquinoline effective against PCP when given in combination with clindamycin.
Araújo, Maria João   +7 more
core  

Efficiency of Histidine Rich Protein II-Based Rapid Diagnostic Tests for Monitoring Malaria Transmission Intensities in an Endemic Area [PDF]

open access: yes, 2018
In recent years there has been a global decrease in the prevalence of malaria due to scaling up of control measures, hence global control efforts now target elimination and eradication of the disease.
Adebayo, H. A.   +7 more
core   +1 more source

Transmission Raman Spectroscopy (TRS) for Accurate Authentication of API in Coated Hydroxychloroquine (HCQ) Tablets

open access: yesJournal of Raman Spectroscopy, EarlyView.
We report the development and use of a transmission Raman spectroscopy (TRS) system for a more accurate but nonintrusive way of authentication of API in coated HCQ tablets which otherwise is not possible using the backscattered (BS) configuration of Raman spectroscopy. The coating interference is found to be almost zero in case of the TRS and a greater
Vijay Kumar   +5 more
wiley   +1 more source

Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study

open access: yesThe Lancet Regional Health. Americas, 2022
Summary: Background: Difficulties associated with the assessment of glucose-6-phosphate dehydrogenase deficiency (G6PDd), particularly in remote areas, hinders the safe use of 8-aminoquinolines such as primaquine (PQ) and tafenoquine against Plasmodium ...
Joabi Rocha Nascimento   +17 more
doaj   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

open access: yesSmall, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi   +14 more
wiley   +1 more source

Safety, tolerability, and efficacy of high versus low-dose, short versus long-course daily primaquine for the radical cure of uncomplicated Plasmodium vivax malaria in children under 15 years of age: an open-label, non-inferiority, randomized controlled trial (CHILDPRIM)

open access: yesMalaria Journal
Background Primaquine (PQ) is widely used to prevent Plasmodium vivax relapses. However, the most efficacious and safest dose is unknown, particularly in children.
Ana Luisa O. Pacheco   +21 more
doaj   +1 more source

Changing antimalarial drug resistance patterns identified by surveillance at three sites in Uganda. [PDF]

open access: yes, 2016
: We assessed Plasmodium falciparum drug resistance markers in parasites collected in 2012, 2013, and 2015 at 3 sites in Uganda. The prevalence and frequency of parasites with mutations in putative transporters previously associated with resistance to ...
Asua, V   +14 more
core   +2 more sources

Short‐Course Low‐Dose Primaquine for Radical Cure in G6PD‐Normal Patients in the Pre‐Elimination Context of Nepal

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Plasmodium vivax remains a challenge for malaria elimination in Nepal due to its ability to relapse. Radical cure with primaquine is effective but limited by poor adherence to the standard 14‐day low‐dose regimen. In 2022, the WHO recommended administering the same total dose (3.5 mg/kg) over 7 days to improve adherence.
Prakash Ghimire   +18 more
wiley   +1 more source

Photochrome That Was Not: 2-Hydroxynaphtylidene-(8-aminoquinoline)

open access: yesThe Journal of Physical Chemistry A, 2011
We report the results of quantum-chemical calculations, which show that the keto form of 2-hydroxynaphtylidene-(8-aminoquinoline) (HNAQ) is slightly more stable than the enol form both in the ground and first excited ππ* electronic states. The barrier for proton transfer between the enol and the ketone in the ground state is ca.
Zgierski, Marek Z., Lim, Edward C.
openaire   +3 more sources

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