Results 21 to 30 of about 8,420 (193)
Biomolecules, 2019 Fusarinine C (FSC) has recently been shown to be a promising and novel chelator for 89Zr. Here, FSC has been further derivatized to optimize the complexation properties of FSC-based chelators for 89Zr-labeling by introducing additional carboxylic groups.
Chuangyan Zhai +11 more
doaj +1 more source
Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys. [PDF]
, 2013 These studies focused on a new radiolabeling technique with copper ((64)Cu) and zirconium ((89)Zr) for positron emission tomography (PET) imaging using a CD45 antibody.
Cherry, Simon R +3 more
core +2 more sources
Immunoscintigraphy for therapy decision making and follow-up of biological therapies [PDF]
, 2016 With the availability of new biological therapies there is the need of more accurate diagnostic tools to noninvasively assess the presence of their targets.
Auletta, S. +6 more
core +2 more sources
EJNMMI Physics, 2021 Purpose The aim of this study was to evaluate the use of a Bayesian penalized likelihood reconstruction algorithm (Q.Clear) for 89Zr-immunoPET image reconstruction and its potential to improve image quality and reduce the administered activity of 89Zr ...
Julian Kirchner +3 more
doaj +1 more source
Frontiers in Oncology, 2021 Macrophages can promote tumor development. Preclinically, targeting macrophages by colony-stimulating factor 1 (CSF1)/CSF1 receptor (CSF1R) monoclonal antibodies (mAbs) enhances conventional therapeutics in combination treatments.
Stijn J. H. Waaijer +10 more
doaj +1 more source
New developments in the experimental data for charged particle production of medical radioisotopes [PDF]
, 2015 The goal of the present work is to give a review of developments achieved experimentally in the field of nuclear data for medically important radioisotopes in the last three years.
Ditrói, F. +3 more
core +2 more sources
Optimization of cyclotron production for radiometal of Zirconium 89 [PDF]
, 2015 Zirconium 89 (89Zr) is a promising radionuclide for development of new PET agents due to its convenient half life of 78.4 h, β+ emission rate of 23%, low maximum energy of 0.9 MeV resulting in good spatial resolution, a stable daughter isotope of yttrium-
Dabkowski, Adam M. +3 more
core +3 more sources
Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe [PDF]
, 2017 Staphylococcus aureus infections are a major threat in healthcare, requiring adequate early-stage diagnosis and treatment. This calls for novel diagnostic tools that allow noninvasive in vivo detection of staphylococci.
Ashbaugh, Alyssa G. +16 more
core +9 more sources
Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin [PDF]
Clinical Cancer Research, 2017 Abstract Purpose: mTOR regulates many normal physiological processes and when hyperactive can drive numerous cancers and human diseases. However, it is very challenging to detect and quantify mTOR signaling noninvasively in clinically relevant animal models of disease or man.
Truillet, Charles +7 more
openaire +4 more sources
Molecular Imaging, 2022 We developed an immuno-PET technique that monitors modulation of tumor CD133 expression, which is required for the success of CD133-targeted therapies. Methods. Anti-CD133 antibodies were subjected to sulfhydryl moiety-specific 89Zr conjugation.
Kyung-Ho Jung +5 more
doaj +1 more source