Results 91 to 100 of about 1,574,329 (197)

Target screening and optimization of candidate compounds for breast cancer treatment using bioinformatics and computational chemistry approaches

Frontiers in Pharmacology
ObjectivesThis study aimed to identify critical therapeutic targets and design potent antitumor compounds for breast cancer treatment through an integrated bioinformatics and computational chemistry approach.MethodsWe conducted initial screening and ...
Jian Xu, Xue Li, Yiduo Jia, Yiduo Jia
doaj   +1 more source

A novel genetically modified mouse seizure model for evaluating anticonvulsive and neuroprotective efficacy of an A₁ adenosine receptor agonist following soman intoxication. [PDF]

Toxicol Appl Pharmacol, 2023
Shih TM.
europepmc   +1 more source

Species Differences in Microsomal Metabolism of Xanthine-Derived A₁ Adenosine Receptor Ligands. [PDF]

Pharmaceuticals (Basel), 2021
Schneider D, Bier D, Holschbach M, Bauer A, Neumaier B.   +4 more
europepmc   +1 more source

Dual Inhibition of Ornithine Decarboxylase and A₁ Adenosine Receptor Efficiently Suppresses Breast Tumor Cells. [PDF]

Front Oncol, 2021
Ma H, Li Q, Wang J, Pan J, Su Z, Liu S.
europepmc   +1 more source

Adenosine Receptor A1 [PDF]

, 2020
openaire   +1 more source

A Body of Circumstantial Evidence for the Irreversible Ectonucleotidase Inhibitory Action of FSCPX, an Agent Known as a Selective Irreversible A₁ Adenosine Receptor Antagonist So Far. [PDF]

Int J Mol Sci, 2021
Viczjan G, Erdei T, Ovari I, Lampe N, Szekeres R, Bombicz M, Takacs B, Szilagyi A, Zsuga J, Szilvassy Z, Juhasz B, Gesztelyi R.   +11 more
europepmc   +1 more source

A1 adenosine receptor signaling reduces Streptococcus pneumoniae adherence to pulmonary epithelial cells by targeting expression of platelet-activating factor receptor. [PDF]

Cell Microbiol, 2020
Bhalla M, Hui Yeoh J, Lamneck C, Herring SE, Tchalla EYI, Heinzinger LR, Leong JM, Bou Ghanem EN.   +7 more
europepmc   +1 more source

A₁ Adenosine Receptor Partial Agonists and Allosteric Modulators: Advancing Toward the Clinic? [PDF]

Front Pharmacol, 2020
Vincenzi F, Pasquini S, Battistello E, Merighi S, Gessi S, Borea PA, Varani K.   +6 more
europepmc   +1 more source

Loss of caveolar A1 adenosine receptor signalling blunts anti-adrenergic control in heart failure. [PDF]

Cardiovasc Res
Mazzola M, Wang H, Lang D, Balycheva M, Bhogal N, Sanchez-Alonso JL, Diakonov I, Lucarelli C, Lai EC, Punjabi PP, Miragoli M, Faggian G, Glukhov AV, Gorelik J.   +13 more
europepmc   +1 more source

Bezafibrate prolongs hypothermia induced by an A₁ adenosine receptor agonist in CBA/N mice. [PDF]

J Vet Med Sci
Sato-Hashimoto M, Ohnishi H.
europepmc   +1 more source