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Determination of A1 and A2 β-Casein in Milk Using Characteristic Thermolytic Peptides via Liquid Chromatography-Mass Spectrometry [PDF]

open access: goldMolecules, 2023
β-casein, a protein in milk and dairy products, has two main variant forms termed as A1 and A2. A1 β-casein may have adverse effects on humans. The fact that there is only one amino acid variation at the 67th position between A1 and A2 β-casein makes it ...
Zeyang Liu   +4 more
doaj   +4 more sources

Differential A1/A2 β-casein (CSN2) gene-derived allelic and genotypic frequencies across Ecuadorian exotic dairy cattle breeds [PDF]

open access: goldFrontiers in Veterinary Science
Recently, a growing interest in dairy cattle selection has been triggered due to specific genetic variations of the β-casein (CSN2) gene which was associated to several human disorders.
Luis F. Cartuche-Macas   +6 more
doaj   +4 more sources

Frequency of A1 and A2 alleles of the β-casein gene in cattle in the Cajamarca region of Peru [PDF]

open access: goldOpen Veterinary Journal
Background: Cow's milk β-casein has multiple genetic variants, the two most common of which are A1 and A2, which are encoded by the CSN2 gene. Evidence suggests that the A1 variant may negatively affect human health.
Antuanet Lissett Becerra-Quiroz   +8 more
doaj   +3 more sources

A2 β-casein infant formula with high sn-2 palmitate and casein phosphopeptides (CPP) supports energy and mineral absorption in Chinese infants [PDF]

open access: goldFrontiers in Nutrition
Infant formula (IF) is essential when breastfeeding is not possible or sufficient. We previously reported that, in a randomized, double-blind clinical trial with 180 healthy infants, an A2 β-casein IF containing high sn-2 palmitate levels, and casein ...
Li Wang   +6 more
doaj   +4 more sources

Effects of β-casein A1/A2 milk and β- and κ-casein genotypes on the performance, body composition, and fecal score of dairy calves [PDF]

open access: goldScientific Reports
The perceived health benefits of β-casein (β-CN) A2 milk for humans have driven increased selection for homozygous β-CN A2 dairy cattle. However, little is known about the effects of feeding milk with different β-CN variants to calves, or about the ...
R. Kappes   +8 more
doaj   +4 more sources

Worldwide Research Trends on Milk Containing Only A2 β-Casein: A Bibliometric Study [PDF]

open access: yesAnimals, 2022
The protein fraction of β-casein may play a key role in the manifestation of a new intolerance: milk protein intolerance. The most common forms of β-casein among dairy cattle breeds are A1 and A2 β-casein. During gastrointestinal digestion of A1 β-casein,
Lucía Jiménez-Montenegro   +3 more
doaj   +2 more sources

Post-weaning A1/A2 β-casein milk intake modulates depressive-like behavior, brain μ-opioid receptors, and the metabolome of rats [PDF]

open access: yesiScience, 2021
Summary: The postnatal period is critical for brain and behavioral development and is sensitive to environmental stimuli, such as nutrition. Prevention of weaning from maternal milk was previously shown to cause depressive-like behavior in rats ...
Aya Osman   +8 more
doaj   +2 more sources

Modification of a previously patented method to unequivocally score A2-like and A1-like bovine β-casein variants [PDF]

open access: goldMethodsX, 2023
A growing interest in the production and commercialization of A2 cow's milk has been observed in many countries in the last few years due to the beneficial properties for human health attributed to A2 β-casein variant.
María Agustina Raschia   +3 more
doaj   +2 more sources

Worldwide research on the health effects of bovine milk containing A1 and A2 β-casein: Unraveling the current scenario and future trends through bibliometrics and text mining [PDF]

open access: yesCurrent Research in Food Science, 2023
The possible adverse effect of consuming bovine milk with A1 β-casein (but not with A2 β-casein) on health aspects due to the release of β-casomorphin-7 (BCM-7) is currently under debate.
Jhony Alberto Gonzales-Malca   +4 more
doaj   +2 more sources

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