Results 151 to 160 of about 63,350 (232)

Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the alpha subunit of bacterial luciferase [PDF]

, 1985
The nucleotide sequence of the 1.85-kilobase EcoRI fragment from Vibrio harveyi that was cloned using a mixed-sequence synthetic oligonucleotide probe (Cohn, D. H., Ogden, R. C., Abelson, J. N., Baldwin, T. O., Nealson, K. H., Simon, M.
Baldwin, Thomas O., Bonam, Duane, Cohn, Daniel H., Mileham, Alan J., Nealson, Kenneth H., Rausch, Steven K., Simon, Melvin I.   +6 more
core  

Quality control of protein import into mammalian mitochondria

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondrial function depends on the continuous import of hundreds of nuclear‐encoded proteins. Targeting and translocation of mitochondrial proteins is a multistep process that is inherently vulnerable to defects in cytosolic quality control systems as well as perturbations in mitochondrial protein import machinery and organelle function ...
Madeleine Goldstein, Laurie Lee‐Glover, Hilla Weidberg   +2 more
wiley   +1 more source

Pathogenicity and Antimicrobial‐Resistance Profiles of Escherichia coli Isolated From Faeces of Tibetan Pigs Reared Under Intensive Conditions

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Tibetan pig farms host diverse Escherichia coli strains that resist multiple antibiotics and carry important disease genes, such as astA. These traits jump easily between bacterial groups, marking intensive pig production as a key reservoir and signalling the need for integrated animal–human surveillance and more careful antibiotic use.
Runbo Luo, Lihong Zhang, Kexin Li, Yanan Zhong, Peng Shang, Suolang Sizhu, Md. F. Kulyar, Ruibing Cao   +7 more
wiley   +1 more source

The cytoplasmic domain of the AAA+ protease FtsH is tilted with respect to the membrane to facilitate substrate entry. [PDF]

J Biol Chem, 2021
Carvalho V, Prabudiansyah I, Kovacik L, Chami M, Kieffer R, van der Valk R, de Lange N, Engel A, Aubin-Tam ME.   +8 more
europepmc   +1 more source

Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease [PDF]

, 2020
The proteasome is the central component of the main cellular protein degradation pathway. During the past four decades, the critical function of the proteasome in numerous physiological processes has been revealed, and proteasome activity has been linked
Li, Jing, Sherman, David J.
core  

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

Extracellular RNA as a molecular driver and therapeutic target in abdominal aortic aneurysms

Scientific Reports
Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammation, matrix degradation and smooth muscle cell (SMC) loss, leading to vessel dilation and rupture, with no current pharmaceutical management options.
Nahla Ibrahim, Hubert Hayden, Gabriel Kurzreiter, Johannes Klopf, Sonja Bleichert, Tyler Artner, Alexander Stiglbauer-Tscholakoff, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan   +9 more
doaj   +1 more source

Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis

mBio
Chlamydia is an obligate intracellular bacterium that undergoes a complex biphasic developmental cycle, alternating between the smaller, infectious, non-dividing elementary body (EB) and the larger, non-infectious but dividing reticulate body. Due to the
Aaron A. Jensen, Saba Firdous, Lei Lei, Derek J. Fisher, Scot P. Ouellette   +4 more
doaj   +1 more source

Stress Granule‐Associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3371-3390, May 2026.
ABSTRACT The escalating global temperatures and intensifying heat stress events pose significant threats to maize productivity worldwide. Uncovering key thermotolerance genes and their functional mechanisms is thus critical for developing climate‐resilient crops.
Yufang Xu, Yudong Fan, Yulian Li, Yilin Zhang, Enpeng Liu, Ruiqi Li, Peipei Ma, Tao Li, Huiyong Zhang   +8 more
wiley   +1 more source

Fully Tunable Phosphorylation of RPS6A Ensures the Successful Development of Arabidopsis Seedlings

Plant, Cell &Environment, Volume 49, Issue 5, Page 2783-2794, May 2026.
ABSTRACT Light enhances protein translation, enabling young seedlings to rapidly and timely acquire photosynthetic capacities. Sequential phosphorylation of ribosomal protein S6 (RPS6) was implicated in the light‐enhanced translation; however, the exact phosphorylation sites and the biological relevance of RPS6 multi‐phosphorylation in seedling ...
Yueh Cho, Guan‐Hong Chen, Shu‐Hsing Wu   +2 more
wiley   +1 more source