Results 91 to 100 of about 3,204 (212)

Abrin-induced apoptosis activates caspase -2, -8 and -3.

, 2014
(A) Jurkat cells were treated with abrin (10 ng/ml) for different time intervals (0–10 h). After the treatment, whole cell lysates were prepared and analysed by Western blot for cleaved caspase-2, -8, -3 and Bid using specific antibodies.
Ritu Mishra (541530), Anjali A. Karande (385296)   +1 more
core   +1 more source

Acute disseminated encephalomyelitis due to abrus precatorius poisoning – A case report

Saudi Pharmaceutical Journal, 2019
Abrus precatorius, commonly known as ‘Rosary pea’ or ‘Jequirity pea’ and known as ‘Shisham, Batrah-Hindi or Ain Alfreeth’ in the Middle East, grows wild in the tropical and subtropical areas of the world.
Elizabeth C. Ninan, Emmanuel James
doaj   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

Toxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova, Jana Klimentova, Alena Fucikova, Jiri Dresler   +3 more
doaj   +1 more source

Toxicity and Detection of Ricin and Abrin in Beverages

Journal of Food Protection, 2008
The oral and intraperitoneal (i.p.) toxicities to female BALB/c mice of ricin and abrin in phosphate-buffered saline (PBS), spring water, apple juice, and half-and-half (only oral) were examined after brief (2 h) and prolonged (11 to 13 days) storage. The ricin and abrin samples prepared in PBS had oral toxicities consistent with those previous studies,
openaire   +2 more sources

The effect of pH on the unfolding pathway and stability of ribosome-inactivating protein abrin-II

, 1998
The effect of pH on the unfolding pathway and the stability of the toxic protein abrin-II have been studied by increasing denaturant concentrations of guanidine hydrochloride and by monitoring the change in 8,1-anilino naphthalene sulfonic acid (ANS ...
Krupakar, Jayarapu, Das, Puspendu K., Podder, Sunil K.   +2 more
core   +2 more sources

Abrin P2 suppresses proliferation and induces apoptosis of colon cancer cells via mitochondrial membrane depolarization and caspase activation

, 2016
To explore the cytotoxic mechanism of abrin P2 on human colon cancer HCT-8 cells, abrin P2 was isolated from the seed of Abrus precatorius L. It was found that abrin P2 exhibited cytotoxicity toward 12 different human cancer cell lines.
Zhaoyang Liu, Xiuyun Zhao, Gao, Nannan, Ying Yu, Song, Xin, Liu, Zhaoyang, Xin Song, Liqin Li, Li, Liqin, Dandan Qin, Fang Liu, Runmei Yang, Nannan Gao, Yang, Runmei, Qin, Dandan, Renqing Feng, Yu, Ying, Zhao, Xiuyun, Liu, Fang, Feng, Renqing   +19 more
core   +1 more source

Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10 [PDF]

, 2014
Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond.
Mishra, Ritu
core  

Evaluation of codA, tms2, and ABRIN-A as negative selectable markers in transgenic tobacco and rice

, 2014
© 2014, The Society for In Vitro Biology. The codA and tms2 genes are used as efficient conditional negative selectable markers (NSMs) in several dicotyledonous plants.
Veluthambi, Karuppannan, Majhi, Bharat Bhusan, Jawkar, Saroj, Bhosale, Rahul   +3 more
core   +1 more source

Performance of Classification Models of Toxins Based on Raman Spectroscopy Using Machine Learning Algorithms. [PDF]

Molecules, 2023
Zhang P, Liu B, Mu X, Xu J, Du B, Wang J, Liu Z, Tong Z.   +7 more
europepmc   +1 more source

Understanding the efficiency of Shodhana, a classical drug detoxification technique that may increase safety in using three varieties of Abrus precatorius L. seeds-a toxic Schedule E1 drug used in various herbal formulations

Phytomedicine Plus
Background: Abrus precatorius L. is a noxious vein native to south east asia and popularly called as Gunja in Ayurveda. The seeds of this plant are considered as a potent raw drug used in various herbal formulations such as Gunjadi tailam, Gunjagarbha ...
Vikram E N T, Kamaraj R, Ilavarasan R, Kusuma G, Susikumar Sundharamoorthy, Ch V. Narasimhaji, Gokul Marimuthu   +6 more
doaj   +1 more source