Results 91 to 100 of about 2,553 (186)

Abrin mediated protein synthesis inhibition and apoptosis in Jurkat cells.

open access: yes, 2014
(A) Jurkat cells were treated with different concentrations of abrin for 8 h and protein synthesis was measured by incorporation of [3H]-leucine. (B) Jurkat cells were treated with varying concentrations (16 nM – 0.016 nM) of abrin for 12 h.
Ritu Mishra (541530)   +1 more
core   +1 more source

Protein Biotoxins of Military Significance

open access: yesActa Medica, 2006
There is a spectrum of several threat agents, ranging from nerve agents and mustard agents to natural substances, such as biotoxins and new, synthetic, bioactive molecules produced by the chemical industry, to the classical biological warfare agents. The
Jiří Patočka, Ladislav Středa
doaj   +1 more source

Acute disseminated encephalomyelitis due to abrus precatorius poisoning – A case report

open access: yesSaudi Pharmaceutical Journal, 2019
Abrus precatorius, commonly known as ‘Rosary pea’ or ‘Jequirity pea’ and known as ‘Shisham, Batrah-Hindi or Ain Alfreeth’ in the Middle East, grows wild in the tropical and subtropical areas of the world.
Elizabeth C. Ninan, Emmanuel James
doaj   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

open access: yesToxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova   +3 more
doaj   +1 more source

Abrin-induced apoptosis activates caspase -2, -8 and -3.

open access: yes, 2014
(A) Jurkat cells were treated with abrin (10 ng/ml) for different time intervals (0–10 h). After the treatment, whole cell lysates were prepared and analysed by Western blot for cleaved caspase-2, -8, -3 and Bid using specific antibodies.
Ritu Mishra (541530)   +1 more
core   +1 more source

Ribosome-Inactivating Proteins from Plants: A Historical Overview

open access: yesMolecules, 2016
This review provides a historical overview of the research on plant ribosome-inactivating proteins (RIPs), starting from the first studies at the end of eighteenth century involving the purification of abrin and ricin, as well as the immunological ...
Andrea Bolognesi   +4 more
doaj   +1 more source

Abrin P2 suppresses proliferation and induces apoptosis of colon cancer cells via mitochondrial membrane depolarization and caspase activation

open access: yes, 2016
To explore the cytotoxic mechanism of abrin P2 on human colon cancer HCT-8 cells, abrin P2 was isolated from the seed of Abrus precatorius L. It was found that abrin P2 exhibited cytotoxicity toward 12 different human cancer cell lines.
Zhaoyang Liu   +19 more
core   +1 more source

The effect of pH on the unfolding pathway and stability of ribosome-inactivating protein abrin-II

open access: yes, 1998
The effect of pH on the unfolding pathway and the stability of the toxic protein abrin-II have been studied by increasing denaturant concentrations of guanidine hydrochloride and by monitoring the change in 8,1-anilino naphthalene sulfonic acid (ANS ...
Krupakar, Jayarapu   +2 more
core   +2 more sources

Evaluation of codA, tms2, and ABRIN-A as negative selectable markers in transgenic tobacco and rice

open access: yes, 2014
© 2014, The Society for In Vitro Biology. The codA and tms2 genes are used as efficient conditional negative selectable markers (NSMs) in several dicotyledonous plants.
Veluthambi, Karuppannan   +3 more
core   +1 more source

Toxicity and Detection of Ricin and Abrin in Beverages

open access: yesJournal of Food Protection, 2008
The oral and intraperitoneal (i.p.) toxicities to female BALB/c mice of ricin and abrin in phosphate-buffered saline (PBS), spring water, apple juice, and half-and-half (only oral) were examined after brief (2 h) and prolonged (11 to 13 days) storage. The ricin and abrin samples prepared in PBS had oral toxicities consistent with those previous studies,
openaire   +2 more sources

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