Results 71 to 80 of about 3,204 (212)
Advancement of abrin toxin bioforensics capabilities
, 2021 Abrin toxin, located in the seeds of Abrus precatorius, is a potent Type II Ribosome-Inactivating Protein (RIP) A-B subunit toxin that has acquired a heightened biothreat profile over the past decade. Significant research efforts must be made in order to
Klassen, Matthew William
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Quantification of Ricinine and Abrine in Human Plasma by HPLC–MS-MS: Biomarkers of Exposure to Ricin and Abrin [PDF]
Journal of Analytical Toxicology, 2018 Ricin and abrin are toxic ribosome-inactivating proteins found in plants. Exposure to these toxins can be detected using the biomarkers ricinine and abrine, which are present in the same plant sources as the toxins. The concentration of the biomarkers in urine and blood will be dependent upon the purification of abrin or ricin, the route of exposure ...
Samantha L Isenberg +8 more
openaire +2 more sources
Molecules, 2016 Peptide capture agents have become increasingly useful tools for a variety of sensing applications due to their ease of discovery, stability, and robustness.
Deborah A. Sarkes +2 more
doaj +1 more source
Chemical Modification of Tryptophan Residues in Abrin-a.
Agricultural and Biological Chemistry, 1991 Chemical modification of tryptophan residues in abrin-a with N-bromosuccinimide (NBS) was studied with regard to saccharide-binding. The number of tryptophan residues available for NBS oxidation increased with lowering pH, and 11 out of the 13 tryptophan residues in abrin-a were eventually modified with NBS at pH 4.0, while 6 tryptophan residues were ...
OHBA, Hideki +2 more
openaire +2 more sources
Abrin Poisoning in an 18-Month-Old Child [PDF]
American Journal of Case Reports, 2015 When discussing known poisons and their clinical consequences, few physicians are aware of the deadly poison abrin. The common symptoms of abrin toxicity include nausea, vomiting, abdominal pain, and diarrhea with or without bloody stool. However, with an estimated fatal human dose of less than 1 microgram/kg, death due to complications such as liver ...
Alhamdani, Mazin +2 more
openaire +2 more sources
Influence of Food Matrices on the Stability and Bioavailability of Abrin
Toxins, 2018 Abrin, a highly toxic plant toxin, is a potential bioterror weapon. Work from our laboratory and others have shown that abrin is highly resistant to both thermal and pH inactivation methods.
Christina C. Tam +3 more
doaj +1 more source
FACT SHEET : Interim Document, 7\uad2\uad03What abrin is\u25cf Abrin is a natural poison that is found in the seeds of a plant called the rosary pea or jequirity pea. These seeds are red with a black spot covering one end.\u25cf Abrin is similar to ricin,
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Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins
Toxins, 2020 Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of ...
Christopher Pöhlmann, Thomas Elßner
doaj +1 more source
Immunoneutralization Of Cytotoxic Abrin : Insights Into Mechanisms And Therapy [PDF]
, 2012 Type II Ribosome Inactivating Proteins (RIPs), commonly known as A/B toxins are heterodimers comprising of a catalytically active A chain, an RNA N-glycosidase which inhibits protein synthesis and a lectin-like B chain required for the binding of the ...
Bagaria, Shradha
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Abrin induces ER stress in Jurkat cells.
, 2014 (A) After the treatment of Jurkat cells with abrin (10 ng/ml) for different time intervals (0–10 h), whole cell lysates were prepared and analysed by Western blot for the total and phosphorylated levels of eIF2α, JNK and p38 MAPK using specific ...
Ritu Mishra (541530) +1 more
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