Results 51 to 60 of about 2,553 (186)
A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Kenya’s vision 2030 partly aims at ensuring adequate health care for all, and the integration of traditional healthcare practices into the national healthcare system would present a more rapid alternative towards the realization of universal health coverage in Kenya.
Elizabeth A. Odongo +4 more
wiley +1 more source
Nano‐Oncologicals: A Tortoise Trail Reaching New Avenues
Advanced Functional Materials, Volume 31, Issue 44, October 26, 2021., 2021 This is a critical review of the applications of nanotechnology for the improvement of oncological treatments based both on synthetic and biological molecules to target either tumor or immune cells. An overview of the early beginnings of the field, together with the most relevant formulations in clinical and preclinical evaluation, is also provided ...
Tamara G. Dacoba +8 more
wiley +1 more source
New Immunotherapeutic Approaches for Glioblastoma
Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021 Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality rate. The current treatment consists of surgical resection, radiation, and chemotherapy; however, the median survival rate is only 12–18 months despite these alternatives, highlighting the urgent need to find new strategies.
Gustavo Ignacio Vázquez Cervantes +5 more
wiley +1 more source
Biodefense against Abrin and Ricin as bioterrorism agents - a virtual screening of Indonesian plant medicinal properties [PDF]
, 2022 Because of their high lethality and easy way to produce, abrin and ricin are often used as bioweapons. Sources of raw materials for the abrin and ricin manufacture can be found in various regions, especially in tropical countries.
Timbul Siahaan +2 more
core +1 more source
Llama-Derived Single Domain Antibodies Specific for Abrus Agglutinin
Toxins, 2011 Llama derived single domain antibodies (sdAb), the recombinantly expressed variable heavy domains from the unique heavy-chain only antibodies of camelids, were isolated from a library derived from llamas immunized with a commercial abrin toxoid ...
James P. Carney +10 more
doaj +1 more source
선진국방연구, 2023 Increasing non-traditional threats from biological or chemical weapons, the Organisation for the Prohibition of Chemical Weapons (OPCW) have tried to perform the preliminary analysis of biotoxin sample to standardize analysis methods and strengthen ...
Seungmin Kang +4 more
doaj +3 more sources
Biomedical Research Journal, 2017 Abrin is a highly lethal ribosome-inactivating protein of high relevance in bio-warfare. Neutralizing antibodies to abrin reported so far afford protection in a very small window with no rescue observed post-abrin exposure.
Meenakshi Sundaram Kumar +3 more
doaj +1 more source
, 2006 Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein synthesis in eukaryotic cells.
Bagaria, A. +4 more
core +2 more sources
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Toxins, 2022 The compound EACC (ethyl (2-(5-nitrothiophene-2-carboxamido) thiophene-3-carbonyl) carbamate) was recently reported to inhibit fusion of autophagosomes with lysosomes in a reversible manner by inhibiting recruitment of syntaxin 17 to autophagosomes.
Kirsten Sandvig +4 more
doaj +1 more source
Engineering in Life Sciences, Volume 20, Issue 11, Page 494-503, November 2020., 2020 Abstract Shiga toxin‐producing Escherichia coli (STEC) infection causes a series of diseases that are highly pathogenic and deadly in humans and animals, seriously endangering public health. Of the pathogenic factors within STEC, the two groups of Shiga toxin (Stx) consisting Stx1 and Stx2 plays a prominent role in the pathogenesis of STEC infection ...
Qiaozhen Wei +10 more
wiley +1 more source