Results 41 to 50 of about 4,965 (233)

A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Kenya’s vision 2030 partly aims at ensuring adequate health care for all, and the integration of traditional healthcare practices into the national healthcare system would present a more rapid alternative towards the realization of universal health coverage in Kenya.
Elizabeth A. Odongo   +4 more
wiley   +1 more source

Nano‐Oncologicals: A Tortoise Trail Reaching New Avenues

open access: yesAdvanced Functional Materials, Volume 31, Issue 44, October 26, 2021., 2021
This is a critical review of the applications of nanotechnology for the improvement of oncological treatments based both on synthetic and biological molecules to target either tumor or immune cells. An overview of the early beginnings of the field, together with the most relevant formulations in clinical and preclinical evaluation, is also provided ...
Tamara G. Dacoba   +8 more
wiley   +1 more source

New Immunotherapeutic Approaches for Glioblastoma

open access: yesJournal of Immunology Research, Volume 2021, Issue 1, 2021., 2021
Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality rate. The current treatment consists of surgical resection, radiation, and chemotherapy; however, the median survival rate is only 12–18 months despite these alternatives, highlighting the urgent need to find new strategies.
Gustavo Ignacio Vázquez Cervantes   +5 more
wiley   +1 more source

Extensive evolution of cereal ribosome-inactivating proteins translates into unique structural features, activation mechanisms, and physiological roles [PDF]

open access: yes, 2017
Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
De Zaeytijd, Jeroen, Van Damme, Els
core   +2 more sources

Special issue: Ribosome-inactivating proteins : commemorative issue in honor of Professor Fiorenzo Stirpe [PDF]

open access: yes, 2017
The family of ribosome-inactivating proteins (RIPs) groups all enzymes (EC.3.2.2.22) with a so-called RIP domain which comprises N-glycosidase activity and enables these proteins to catalytically inactivate ribosomes.[...
Van Damme, Els
core   +3 more sources

Ricin trafficking in plant and mammalian cells [PDF]

open access: yes, 2011
Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike, Spooner, Robert A.
core   +2 more sources

Llama-Derived Single Domain Antibodies Specific for Abrus Agglutinin

open access: yesToxins, 2011
Llama derived single domain antibodies (sdAb), the recombinantly expressed variable heavy domains from the unique heavy-chain only antibodies of camelids, were isolated from a library derived from llamas immunized with a commercial abrin toxoid ...
James P. Carney   +10 more
doaj   +1 more source

Ricin and Abrin as Possible Agents of Bioterror

open access: yesВестник войск РХБ защиты, 2022
Plant toxins – ricin and abrin, obtained in a purified form from the beans of the castor bean and Abrus precatorius respectively, are considered by Western experts as potential damaging agents of a biological nature.
D. V. Pechenkin   +5 more
doaj   +1 more source

Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]

open access: yes, 2011
B
A Babino   +42 more
core   +3 more sources

Review of recently reported Ricin detection techniques focusing on combined immunoassay detection with abrin and saxitoxin in human plasma

open access: yes선진국방연구, 2023
Increasing non-traditional threats from biological or chemical weapons, the Organisation for the Prohibition of Chemical Weapons (OPCW) have tried to perform the preliminary analysis of biotoxin sample to standardize analysis methods and strengthen ...
Seungmin Kang   +4 more
doaj   +3 more sources

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