Mapping Immunodominant Antibody Epitopes of Abrin [PDF]
Antibodies, 2020 Abrin, a toxin isolated from the seeds of Abrus precatorius (jequirity pea) is considered a biological threat agent by the Center for Disease Control and Prevention.
Ron Alcalay +6 more
doaj +4 more sources
A monoclonal antibody to an abrin chimera recognizing a unique epitope on abrin A chain confers protection from abrin-induced lethality [PDF]
Human Vaccines and Immunotherapeutics, 2016 Abrin, obtained from the seeds of Abrus precatorius plant, is a potent toxin belonging to the family of type II ribosome-inactivating proteins. Recently, a recombinant vaccine consisting of the A subunits of abrin and its homolog Abrus precatorius ...
Anjali A Karande
exaly +5 more sources
CCD Based Detector for Detection of Abrin Toxin Activity
Toxins, 2020 Abrin is a highly potent and naturally occurring toxin produced in the seeds of Abrus precatorius (Rosary Pea) and is of concern as a potential bioterrorism weapon.
Reuven Rasooly +2 more
doaj +3 more sources
Ricin and Abrin as Possible Agents of Bioterror
Вестник войск РХБ защиты, 2022 Plant toxins – ricin and abrin, obtained in a purified form from the beans of the castor bean and Abrus precatorius respectively, are considered by Western experts as potential damaging agents of a biological nature.
D. V. Pechenkin +5 more
doaj +3 more sources
Equal Neutralization Potency of Antibodies Raised against Abrin Subunits
Antibodies, 2020 Abrin and ricin are potent AB toxins, which are considered biological threats. To date, there are no approved treatments against abrin or ricin intoxications.
Yoav Gal +9 more
doaj +2 more sources
Polyclonal antibodies towards abrin and ricin-design and potential application for mass spectrometry-based analysis of human biosamples. [PDF]
Arch ToxicolThe analysis of highly toxic proteins such as abrin and ricin is challenging but comprehensive analytical methods are essential for their unambiguous identification after ingestion.
Vollmer AC +7 more
europepmc +2 more sources
Mass Spectrometric Detection and Differentiation of Enzymatically Active Abrin and Ricin Combined with a Novel Affinity Enrichment Technique. [PDF]
Chem Res ToxicolAbrin and ricin are toxic proteins produced by plants. Both proteins are composed of two subunits, an A-chain and a B-chain. The A-chain is responsible for the enzymatic activity, which causes toxicity.
Drinkard KK, Barr JR, Kalb SR.
europepmc +2 more sources
Mechanistic insights into the neutralization of cytotoxic abrin by the monoclonal antibody D6F10. [PDF]
PLoS ONE, 2013 Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin.
Shradha Bagaria +3 more
doaj +2 more sources
선진국방연구, 2023 Increasing non-traditional threats from biological or chemical weapons, the Organisation for the Prohibition of Chemical Weapons (OPCW) have tried to perform the preliminary analysis of biotoxin sample to standardize analysis methods and strengthen ...
Seungmin Kang +4 more
doaj +4 more sources
Chemosensors, 2022 Abrin is a cytotoxin with strong lethality, which is a serious threat to human health and public safety, and thus, highly sensitive detection methods are urgently needed.
Shuai Liu +9 more
doaj +2 more sources