Toxins, 2018 Abrin toxin is a type 2 ribosome inactivating glycoprotein isolated from the seeds of Abrus precatorius (jequirity pea). Owing to its high toxicity, relative ease of purification and accessibility, it is considered a biological threat agent.
Adva Mechaly +2 more
exaly +4 more sources
A Glycoprotein-Based Surface-Enhanced Raman Spectroscopy–Lateral Flow Assay Method for Abrin and Ricin Detection [PDF]
ToxinsAbrin and ricin, both type II ribosome-inactivating proteins, are toxins of significant concern and are under international restriction by the Chemical Weapons Convention and the Biological and Toxin Weapons Convention.
Lan Xiao +8 more
doaj +3 more sources
A Case of Poisoning with Abrus precatarius Complicated with Bilateral Basal Ganglia Haemorrhage [PDF]
Case Reports in Neurological Medicine, 2022 Abrus precatarius is a tropical climber, whose seeds contain abrin, which is known to cause toxicity in humans. We report a case of a young girl, who presented with haemorrhagic enterocolitis, bilateral septal vein thrombosis, and basal ganglia ...
Arun Rajaratnam +3 more
doaj +3 more sources
Defense and Security Studies, 2022 Because of their high lethality and easy way to produce, abrin and ricin are often used as bioweapons. Sources of raw materials for the abrin and ricin manufacture can be found in various regions, especially in tropical countries.
Leni Tria Melati +2 more
doaj +4 more sources
Rapid Differential Detection of Abrin Isoforms by an Acetonitrile- and Ultrasound-Assisted On-Bead Trypsin Digestion Coupled with LC-MS/MS Analysis [PDF]
Toxins, 2021 The high toxic abrin from the plant Abrus precatorius is a type II ribosome-inactivating protein toxin with a human lethal dose of 0.1–1.0 µg/kg body weight.
Long-Hui Liang +6 more
doaj +3 more sources
Abrin Toxin Paradoxically Increases Protein Synthesis in Stimulated CD4+ T-Cells While Decreasing Protein Synthesis in Kidney Cells [PDF]
Current Issues in Molecular BiologyAbrin, a toxin of the rosary pea plant (Abras precatorius), has been implicated as causing an autoimmune demyelinating disease in humans, but the exact mechanisms responsible for the induction of these demyelinating conditions are still unknown.
Bradley Hernlem, Reuven Rasooly
doaj +3 more sources
Abrin Toxicity and Bioavailability after Temperature and pH Treatment
Toxins, 2017 Abrin, one of most potent toxins known to man, is derived from the rosary pea (jequirity pea), Abrus precatorius and is a potential bioterror weapon.
Larry H Stanker +2 more
exaly +5 more sources
A Self-Driven Microfluidic Chip for Ricin and Abrin Detection [PDF]
Sensors, 2022 Ricin and abrin are phytotoxins that can be easily used as biowarfare and bioterrorism agents. Therefore, developing a rapid detection method for both toxins is of great significance in the field of biosecurity.
Xuexin Bai +13 more
doaj +3 more sources
Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices [PDF]
Toxins, 2021 The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification of low abrin concentrations in ...
Sandrine Livet +7 more
doaj +3 more sources
A New Method for Abrin Detection Based on the Interaction between Target Molecules and Fluorescently Labeled Aptamers on Magnetic Microspheres. [PDF]
Materials (Basel), 2022 A quantitative structure–activity relationship (QSAR) model for the structure and affinity of abrin aptamers was established. A higher affinity abrin aptamer based on the established QSAR model was screened by site-directed mutagenesis.
Liu Z +9 more
europepmc +3 more sources