A Novel Humanized Anti-Abrin A Chain Antibody Inhibits Abrin Toxicity In Vitro and In Vivo [PDF]
Frontiers in Immunology, 2022 Abrin, a type-II ribosome inactivating protein from the seed of Abrus precatorius, is classified as a Category B bioterrorism warfare agent. Due to its high toxicity, ingestion by animals or humans will lead to death from multiple organ failure ...
Jingyi Peng +15 more
doaj +4 more sources
Toxins, 2018 Abrin toxin is a type 2 ribosome inactivating glycoprotein isolated from the seeds of Abrus precatorius (jequirity pea). Owing to its high toxicity, relative ease of purification and accessibility, it is considered a biological threat agent.
Ohad Mazor, Noam Cohen, Tal Noy Porat
exaly +4 more sources
Characterization of Lung Injury following Abrin Pulmonary Intoxication in Mice: Comparison to Ricin Poisoning [PDF]
Toxins, 2022 Abrin is a highly toxic protein obtained from the seeds of the rosary pea plant Abrus precatorius, and it is closely related to ricin in terms of its structure and chemical properties.
Anita Sapoznikov +6 more
doaj +3 more sources
Neutralizing Monoclonal Antibody, mAb 10D8, Is an Effective Detoxicant against Abrin-a Both In Vitro and In Vivo [PDF]
Toxins, 2022 Abrin is a types II ribosome-inactivating protein (RIP) isolated from Abrus precatorious seeds, which comprises a catalytically active A chain and a lectin-like B chain linked by a disulfide bond.
Zhi Li +8 more
doaj +3 more sources
Mapping Immunodominant Antibody Epitopes of Abrin [PDF]
Antibodies, 2020 Abrin, a toxin isolated from the seeds of Abrus precatorius (jequirity pea) is considered a biological threat agent by the Center for Disease Control and Prevention.
Ron Alcalay +6 more
doaj +4 more sources
Differentiation, Quantification and Identification of Abrin and Abrus precatorius Agglutinin [PDF]
Toxins, 2021 Abrin, the toxic lectin from the rosary pea plant Abrus precatorius, has gained considerable interest in the recent past due to its potential malevolent use.
Sylvia Worbs +9 more
doaj +4 more sources
Abrin Toxicity and Bioavailability after Temperature and pH Treatment
Toxins, 2017 Abrin, one of most potent toxins known to man, is derived from the rosary pea (jequirity pea), Abrus precatorius and is a potential bioterror weapon.
Luisa Cheng +2 more
exaly +5 more sources
N-Glycosylation Profile of Abrin Certified EU Reference Material [PDF]
ToxinsAbrin is a highly toxic plant protein encompassing four isoforms, abrin-a, -b, -c and -d. An abrin reference material was isolated from Abrus precatorius and certified (EURM-113) by the EuroBioTox consortium.
Roland Josuran +6 more
doaj +3 more sources
A Case of Poisoning with Abrus precatarius Complicated with Bilateral Basal Ganglia Haemorrhage [PDF]
Case Reports in Neurological Medicine, 2022 Abrus precatarius is a tropical climber, whose seeds contain abrin, which is known to cause toxicity in humans. We report a case of a young girl, who presented with haemorrhagic enterocolitis, bilateral septal vein thrombosis, and basal ganglia ...
Arun Rajaratnam +3 more
doaj +3 more sources
CCD Based Detector for Detection of Abrin Toxin Activity
Toxins, 2020 Abrin is a highly potent and naturally occurring toxin produced in the seeds of Abrus precatorius (Rosary Pea) and is of concern as a potential bioterrorism weapon.
Reuven Rasooly, Paula Do
exaly +4 more sources