Results 31 to 40 of about 4,965 (233)
A Case of Abrin Toxin Poisoning, Confirmed via Quantitation of l-Abrine (N-Methyl-l-Tryptophan) Biomarker [PDF]
Journal of Medical Toxicology, 2014 The seeds of Abrus precatorius contain the highly toxic plant protein abrin. There is no antidote for abrin poisoning. Management, largely supportive, may consist of administering intravenous fluids, anti-emetics, and activated charcoal depending on the time of exposure.
Joe V. Wooten +6 more
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Defense and Security Studies, 2022 Because of their high lethality and easy way to produce, abrin and ricin are often used as bioweapons. Sources of raw materials for the abrin and ricin manufacture can be found in various regions, especially in tropical countries.
Leni Tria Melati +2 more
doaj +1 more source
Mechanistic insights into the neutralization of cytotoxic abrin by the monoclonal antibody D6F10. [PDF]
PLoS ONE, 2013 Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin.
Shradha Bagaria +3 more
doaj +1 more source
Blood microsampling technologies: Innovations and applications in 2022
Analytical Science Advances, Volume 4, Issue 5-6, Page 154-180, July 2023., 2023 Abstract With the development of highly sensitive bioanalytical techniques, the volume of samples necessary for accurate analysis has reduced. Microsampling, the process of obtaining small amounts of blood, has thus gained popularity as it offers minimal‐invasiveness, reduced logistical costs and biohazard risks while simultaneously showing increased ...
Manchu Umarani Thangavelu +4 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023 Sexual disorders such as erectile dysfunction (ED), sterility, and sexual inappetence represent some of the complex reproductive challenges that require addressing the underlying causes. The aim of this paper was to systematically synthesize literature on the ethnobotany, phytochemistry, bioactivities, and safety of plants used as remedies for managing
Christine Kyarimpa +7 more
wiley +1 more source
International Journal of Food Science, Volume 2023, Issue 1, 2023., 2023 Some plant foods evolve defense mechanisms to protect themselves from predators by producing inherent chemicals as secondary metabolites such as cyanogenic glycosides, glycoalkaloids, glucosinolates, pyrrolizidine alkaloids, and lectins. These metabolites are beneficial for the plant itself but toxic to other organisms, including human beings.
Markos Makiso Urugo +2 more
wiley +1 more source
The Plant Genome, Volume 15, Issue 3, September 2022., 2022 Abstract Abrus cantoniensis Hance, a native medicinal plant in southern China, is officially recorded in the Chinese Pharmacopoeia. Here, we presented the first high‐quality genome in Abrus genus, A. cantoniensis genome, as well as the detailed genomic information.
Shiqiang Xu +5 more
wiley +1 more source
Surface‐enhanced Raman scattering: An emerging tool for sensing cellular function
WIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 4, July/August 2022., 2022 SERS is a rapid, ultrasensitive, noninvasive, and versatile technique for biomedical and diagnostics applications. Abstract Continuous long‐term intracellular imaging and multiplexed monitoring of biomolecular changes associated with key cellular processes remains a challenge for the scientific community.
Swati Tanwar +3 more
wiley +1 more source
Journal of Oncology, Volume 2022, Issue 1, 2022., 2022 Background. Liver cancer is the most malignant type of human malignancies. In recent years, immune therapy that targets the immune check points such as programmed cell death ligand 1 (PD‐L1) has achieve great success. Abrine is the dominant alkaloid in Abrus cantoniensis and Abrus precatorius Linn. that exhibited anticancer effect.
Shaowu Zhang, Shangxiang Chen
wiley +1 more source
Effect of Abrin on Peptide Chain Initiation [PDF]
European Journal of Biochemistry, 1977 Cell‐free systems from wheat germ were preincubated before and after addition of immunoglobulin mRNA to generate systems dependent and independent on peptide chain initiation, respectively. When abrin A chain was added, the system dependent on peptide chain initiation was much more strongly inhibited than the system measuring primarily chain elongation.
Jon Skorve +3 more
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