Results 81 to 90 of about 2,553 (186)
Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins
Toxins, 2020 Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of ...
Christopher Pöhlmann, Thomas Elßner
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Immunoneutralization Of Cytotoxic Abrin : Insights Into Mechanisms And Therapy [PDF]
, 2012 Type II Ribosome Inactivating Proteins (RIPs), commonly known as A/B toxins are heterodimers comprising of a catalytically active A chain, an RNA N-glycosidase which inhibits protein synthesis and a lectin-like B chain required for the binding of the ...
Bagaria, Shradha
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Abrin induces ER stress in Jurkat cells.
, 2014 (A) After the treatment of Jurkat cells with abrin (10 ng/ml) for different time intervals (0–10 h), whole cell lysates were prepared and analysed by Western blot for the total and phosphorylated levels of eIF2α, JNK and p38 MAPK using specific ...
Ritu Mishra (541530) +1 more
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Whole-Cell Multiparameter Assay for Ricin and Abrin Activity-Based Digital Holographic Microscopy
Toxins, 2019 Ricin and abrin are ribosome-inactivating proteins leading to inhibition of protein synthesis and cell death. These toxins are considered some of the most potent and lethal toxins against which there is no available antidote.
Efi Makdasi +5 more
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Signaling different pathways of cell death: Abrin induced programmed necrosis in U266B1 cells
, 2010 Abrin is a type II ribosome-inactivating protein comprising of two subunits, A and B. Of the two, the A-subunit harbours the RNA-N-glycosidase activity and the B subunit is a galactose specific lectin that enables the entry of the protein inside the cell.
Sudarshan Gadadhar +5 more
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Journal of Ayurveda and Integrative Medicine, 2014 Background: Abrus precatorius seeds traditionally used for the treatment of sciatica and alopecia contains the toxic protein, abrin, a Type II Ribosome Inactivating Protein.
Sagar B Dhoble, Anuradha S Majumdar
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Effective detoxification of Abrus precatorius Linn. seeds by Shodhana
Journal of Ayurveda and Integrative Medicine, 2013 Ayurveda, which is one of the traditional systems of medicine of India, reports the seeds of Abrus precatorius (family: Fabaceae) can be used therapeutically after shodhana process, which removes the toxin.
Kalyani H Barve, Neha Ojha
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Ricin and abrin are toxic ribosome-inactivating proteins found in plants. Exposure to these toxins can be detected using the biomarkers ricinine and abrine, which are present in the same plant sources as the toxins. The concentration of the biomarkers in
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The mAb D6F10 reduces the binding of abrin on HeLa cells at high concentrations.
, 2013 (A) 500 ng/ml of Alexa-488 labelled abrin was incubated with varying molar concentrations of the mAbs D6F10 or F5B10 or unlabelled abrin for 1 h at 4°C.
Devasena Ponnalagu (438970) +3 more
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Ethno botanical and Phytophrmacological potential of Abrus precatorius L.: A review
Asian Pacific Journal of Tropical Biomedicine, 2014 Medicinal plants are being widely used, either as a single drug or in combination in health care delivery system. Medicinal plants can be important source of previously unknown chemical substances with potential therapeutic effects.
Narendra Garaniya, Atul Bapodra
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