Results 81 to 90 of about 3,204 (212)
Whole-Cell Multiparameter Assay for Ricin and Abrin Activity-Based Digital Holographic Microscopy
Toxins, 2019 Ricin and abrin are ribosome-inactivating proteins leading to inhibition of protein synthesis and cell death. These toxins are considered some of the most potent and lethal toxins against which there is no available antidote.
Efi Makdasi +5 more
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Ricin and abrin are toxic ribosome-inactivating proteins found in plants. Exposure to these toxins can be detected using the biomarkers ricinine and abrine, which are present in the same plant sources as the toxins. The concentration of the biomarkers in
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Signaling different pathways of cell death: Abrin induced programmed necrosis in U266B1 cells
, 2010 Abrin is a type II ribosome-inactivating protein comprising of two subunits, A and B. Of the two, the A-subunit harbours the RNA-N-glycosidase activity and the B subunit is a galactose specific lectin that enables the entry of the protein inside the cell.
Sudarshan Gadadhar +5 more
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Journal of Ayurveda and Integrative Medicine, 2014 Background: Abrus precatorius seeds traditionally used for the treatment of sciatica and alopecia contains the toxic protein, abrin, a Type II Ribosome Inactivating Protein.
Sagar B Dhoble, Anuradha S Majumdar
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Abrin mediated protein synthesis inhibition and apoptosis in Jurkat cells.
, 2014 (A) Jurkat cells were treated with different concentrations of abrin for 8 h and protein synthesis was measured by incorporation of [3H]-leucine. (B) Jurkat cells were treated with varying concentrations (16 nM – 0.016 nM) of abrin for 12 h.
Ritu Mishra (541530) +1 more
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Effective detoxification of Abrus precatorius Linn. seeds by Shodhana
Journal of Ayurveda and Integrative Medicine, 2013 Ayurveda, which is one of the traditional systems of medicine of India, reports the seeds of Abrus precatorius (family: Fabaceae) can be used therapeutically after shodhana process, which removes the toxin.
Kalyani H Barve, Neha Ojha
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The mAb D6F10 reduces the binding of abrin on HeLa cells at high concentrations.
, 2013 (A) 500 ng/ml of Alexa-488 labelled abrin was incubated with varying molar concentrations of the mAbs D6F10 or F5B10 or unlabelled abrin for 1 h at 4°C.
Devasena Ponnalagu (438970) +3 more
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Ethno botanical and Phytophrmacological potential of Abrus precatorius L.: A review
Asian Pacific Journal of Tropical Biomedicine, 2014 Medicinal plants are being widely used, either as a single drug or in combination in health care delivery system. Medicinal plants can be important source of previously unknown chemical substances with potential therapeutic effects.
Narendra Garaniya, Atul Bapodra
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One step Purification and Characterisation of Abrin Toxin from Abrus Precatorius Seeds
, 2019 Abrin is a plant toxin obtained from Abrus precatorius seeds. It belongs to the type II ribosomal inactivating proteins (RIPs) consisting of two chains namely, catalytically active A chain and sugar binding B chain linked by a single disulphide bond ...
Tripathi, Nagesh +4 more
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Protein Biotoxins of Military Significance
Acta Medica, 2006 There is a spectrum of several threat agents, ranging from nerve agents and mustard agents to natural substances, such as biotoxins and new, synthetic, bioactive molecules produced by the chemical industry, to the classical biological warfare agents. The
Jiří Patočka, Ladislav Středa
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