Results 21 to 30 of about 253,180 (311)

Staphylococcal Scalded Skin Syndrome in Neonates: Case Series and Overview of Outbreaks

Antibiotics, 2022
Skin and soft tissue infections caused by Staphylococcus aureus (S. aureus) cover a wide spectrum of diseases in neonates, including staphylococcal scalded skin syndrome (SSSS).
Charlotte M. Nusman, Charlotte Blokhuis, Dasja Pajkrt, Douwe H. Visser   +3 more
doaj   +1 more source

Academic Medical Centers' Standards for Clinical-Trial Agreements With Industry [PDF]

, 2005
BACKGROUND: Although industry sponsors provide approximately 70 percent of the funding for clinical drug trials in the United States, little is known about the legal agreements that exist between industry sponsors and academic investigators.
Studdert, David M., Clarridge, Brian R., Mello, Michelle M.   +2 more
core   +1 more source

Therapeutic application of recombinant human ADAMTS-13 improves shock reversal and coagulation status in a trauma hemorrhage and transfusion rat model

Intensive Care Medicine Experimental, 2020
Introduction In hemorrhaging trauma patients, the endothelium is activated, resulting in excessive endothelial synthesis of von Willebrand Factor (vWF), which may enhance micro-thrombi formation, resulting in obstruction of the microcirculation and ...
Mathijs R. Wirtz, Daan P. van den Brink, Joris J. T. H. Roelofs, J. Carel Goslings, Nicole P. Juffermans   +4 more
doaj   +1 more source

Psychopathological and Neurobiological Overlap Between Anorexia Nervosa and Self-Injurious Behavior: A Narrative Review and Conceptual Hypotheses

Frontiers in Psychiatry, 2022
Empirical evidence and clinical observations suggest a strong -yet under acknowledged-link between anorexia nervosa (AN) and non-suicidal self-injurious behavior (NSSI).
Marloes Oudijn, Jara Linders, Roel Mocking, Anja Lok, Annemarie van Elburg, D. Denys   +5 more
doaj   +1 more source

Health Industry Practices That Create Conflicts of Interest: A Policy Proposal for Academic Medical Centers [PDF]

, 2006
Conflicts of interest between physicians' commitment to patient care and the desire of pharmaceutical companies and their representatives to sell their products pose challenges to the principles of medical professionalism.
Smelser, Neil, Kimball, Harry, Brennan, Troyen A., Blank, Linda, Blumenthal, David, Chimonas, Susan C., Rothman, David J., Naughton, James, Cohen, Jordan J., Goldman, Janlori, Kassirer, Jerome P.   +10 more
core   +1 more source

Induction of Acute or Disseminating Bacterial Pneumonia in Mice and Sampling of Infected Organs for Studying the Host Response to Bacterial Pneumonia

Bio-Protocol, 2022
Experimental pneumonia models are important tools to study the pathophysiology of lung inflammation caused by microbial infections and the efficacy of (novel) drugs.
Wanhai Qin, Zhe Liu, Tom van der Poll, Alex F. de Vos   +3 more
doaj   +1 more source

Improving accountability through alignment: the role of academic health science centres and networks in England. [PDF]

, 2014
BACKGROUND: As in many countries around the world, there are high expectations on academic health science centres and networks in England to provide high-quality care, innovative research, and world-class education, while also supporting wealth creation ...
Wells, Glenn, Buchan, Alastair M, Heitmueller, A, Glenn Wells, Alastair M Buchan, Allen, Pauline, Ovseiko, Pavel V, Darzi, Ara, Buchan, Alastair, Pauline Allen, Darzi, A, Pavel V Ovseiko, Ara Darzi, Buchan, AM, Heitmueller, Axel, Wells, G, Gary A Ford, Davies, SM, Allen, P, Stephen M Davies, Ford, Gary A, Ford, GA, Davies, Stephen M, Axel Heitmueller, Ovseiko, PV   +24 more
core   +1 more source

Bruton’s Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia

Frontiers in Immunology, 2021
Bruton’s tyrosine kinase (Btk) is a cytoplasmic kinase expressed in B cells and myeloid cells. It is essential for B cell development and natural antibody-mediated host defense against bacteria in humans and mice, but little is known about the role of ...
Alexander P. de Porto, Zhe Liu, Zhe Liu, Regina de Beer, Regina de Beer, Sandrine Florquin, Joris J. T. H. Roelofs, Onno J. de Boer, Joke M. M. den Haan, Rudi W. Hendriks, Cornelis van ‘t Veer, Cornelis van ‘t Veer, Tom van der Poll, Tom van der Poll, Tom van der Poll, Alex F. de Vos, Alex F. de Vos   +16 more
doaj   +1 more source

Focused Ethnography of Diagnosis in Academic Medical Centers [PDF]

, 2018
BACKGROUND: Approaches of trainees to diagnosis in teaching hospitals are poorly understood. Identifying cognitive and system-based barriers and facilitators to diagnosis may improve diagnosis in these settings.
Sanjay Saint, Hardeep Singh, Harrod, M, Chopra, V, Molly Harrod, Suzanne Winter, Vineet Chopra, Karen E. Fowler, Forman, J, Krein, S, Sarah Krein, Saint, S, Quinn, M, Jane Forman, Winter, S, Fowler, KE, Singh, H, Martha Quinn   +17 more
core   +1 more source

Myeloid liver kinase B1 contributes to lung inflammation induced by lipoteichoic acid but not by viable Streptococcus pneumoniae

Respiratory Research, 2022
Background Liver kinase B1 (Lkb1, gene name Stk11) functions as a tumor suppressor in cancer. Myeloid cell Lkb1 potentiates lung inflammation induced by the Gram-negative bacterial cell wall component lipopolysaccharide and in host defense during Gram ...
Liza Pereverzeva, Natasja A. Otto, Joris J. T. H. Roelofs, Alex F. de Vos, Tom van der Poll   +4 more
doaj   +1 more source