Results 11 to 20 of about 71,112 (230)

The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis. [PDF]

PLoS Pathogens, 2008
Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using whole-genome Bp microarrays, we examined patterns of gene presence
Siew Hoon Sim, Yiting Yu, Chi Ho Lin, R Krishna M Karuturi, Vanaporn Wuthiekanun, Apichai Tuanyok, Hui Hoon Chua, Catherine Ong, Sivalingam Suppiah Paramalingam, Gladys Tan, Lynn Tang, Gary Lau, Eng Eong Ooi, Donald Woods, Edward Feil, Sharon J Peacock, Patrick Tan   +16 more
doaj   +4 more sources

Evolutionary dynamics of the accessory genome of Listeria monocytogenes.

PLoS ONE, 2013
Listeria monocytogenes, a foodborne bacterial pathogen, is comprised of four phylogenetic lineages that vary with regard to their serotypes and distribution among sources.
Henk C den Bakker, Christopher A Desjardins, Allison D Griggs, Joseph E Peters, Qiandong Zeng, Sarah K Young, Chinnappa D Kodira, Chandri Yandava, Theresa A Hepburn, Brian J Haas, Bruce W Birren, Martin Wiedmann   +11 more
doaj   +4 more sources

ClustAGE: a tool for clustering and distribution analysis of bacterial accessory genomic elements [PDF]

BMC Bioinformatics, 2018
Background The non-conserved accessory genome of bacteria can be associated with important adaptive characteristics that can contribute to niche specificity or pathogenicity of strains.
Egon A. Ozer
doaj   +3 more sources

Assembling telomere-to-telomere genomes of Fusarium oxysporum f. sp. lactucae provides a roadmap for studying genome and phenotype evolution [PDF]

BMC Genomics
Background Accessory genome regions of plant pathogenic fungi, which are highly variable and consist of niche-adaptive genes, play a crucial role in shaping host-specific interactions but are notoriously difficult to assemble.
Ningxiao Li, Jacob L. Steenwyk, Samuel O’Donnell, Emile Gluck-Thaler, Saben M. Kane, David M. Geiser, Frank N. Martin   +6 more
doaj   +2 more sources

Polymorphism and evolutionary origins of accessory chromosomes in the basidiomycete Tremella fuciformis [PDF]

Nature Communications
Accessory chromosomes are non-essential for growth but poorly characterized in basidiomycetes, unlike in Ascomycota. Here, we report whole-genome sequencing of 16 strains of the basidiomycete Tremella fuciformis (silver ear fungus), generating 27 ...
Jinxiang Zhang, Qianwen Tong, Fengjiao Lin, Xingcai An, Haichen Huang, Hualian Chen, Jingjing Ye, Huaizhen Xu, Xiaomeng Lv, Zhiwen Lv, Fangting Zeng, Tuo Zhang, Xiaoping Wu, Baogui Xie, Ray Ming, Youjin Deng   +15 more
doaj   +2 more sources

Comparative genomics links ecological dominance and genome plasticity in sediment-derived Vibrio diabolicus [PDF]

Frontiers in Microbiology
Marine sediments harbor diverse Vibrio populations that play critical roles in benthic microbial ecology; however, the genomic determinants underlying the dominance of sediment-associated Vibrio taxa remain insufficiently characterized at the genome ...
Esmaeil ALSaleh
doaj   +2 more sources

Accessory Genome Dynamics of Local and Global Staphylococcus pseudintermedius Populations. [PDF]

Front Microbiol, 2022
Staphylococcus pseudintermediusis a major bacterial colonizer and opportunistic pathogen in dogs. Methicillin-resistantS. pseudintermedius(MRSP) continues to emerge as a significant challenge to maintaining canine health. We sought to determine the phylogenetic relationships ofS.
Bruce SA, Smith JT, Mydosh JL, Ball J, Needle DB, Gibson R, Andam CP.   +6 more
europepmc   +5 more sources

Detecting patterns of accessory genome coevolution in Staphylococcus aureus using data from thousands of genomes. [PDF]

BMC Bioinformatics, 2023
AbstractBacterial genomes exhibit widespread horizontal gene transfer, resulting in highly variable genome content that complicates the inference of genetic interactions. In this study, we develop a method for detecting coevolving genes from large datasets of bacterial genomes based on pairwise comparisons of closely related individuals, analogous to a
Mehta RS, Petit RA, Read TD, Weissman DB.   +3 more
europepmc   +4 more sources

Transformation Asymmetry and the Evolution of the Bacterial Accessory Genome. [PDF]

Mol Biol Evol, 2018
Bacterial transformation can insert or delete genomic islands (GIs), depending on the donor and recipient genotypes, if an homologous recombination spans the GI's integration site and includes sufficiently long flanking homologous arms. Combining mathematical models of recombination with experiments using pneumococci found GI insertion rates declined ...
Apagyi KJ, Fraser C, Croucher NJ.
europepmc   +6 more sources

Exploring the Accessory Genome of Multidrug-Resistant Rhodococcus equi Clone 2287. [PDF]

Antibiotics (Basel), 2023
Decades of antimicrobial overuse to treat respiratory disease in foals have promoted the emergence and spread of zoonotic multidrug-resistant (MDR) Rhodococcus equi worldwide. Three main R. equi MDR clonal populations—2287, G2106, and G2017—have been identified so far. However, only clones 2287 and G2016 have been isolated from sick animals, with clone
Alvarez Narvaez S, Sanchez S.
europepmc   +4 more sources