Results 111 to 120 of about 146,351 (241)

Stimulation of acetyl‐CoA carboxylase by (−)‐Hydroxycitrate [PDF]

FEBS Letters, 1972
Hackenschmidt, J., Barth, C., Decker, K.
openaire   +2 more sources

We set the objective function of the constructed models to the given reactions (acetyl-CoA synthetase and acetyl-CoA carboxylase reactions) and turned the lower bound to zero for maximizing the production and regulation reaction of acetyl-CoA.

, 2014
The producing reaction of acetyl-CoA is catalyzed by acetyl-CoA synthetase, which is in turn regulated by acetyl-CoA carboxylase, an enzyme which catalyzes acetyl CoA conversion to malonyl-CoA, the first and rate-limiting reaction in de novo synthesis of
Ali Akbar Saboury (233129), Ali Salehzadeh-Yazdi (309592), Yazdan Asgari (489425), Ali Masoudi-Nejad (19213)   +3 more
core   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Constituents of cinnamon inhibit bacterial acetyl CoA carboxylase

, 2010
Cinnamon bark (Cinnamomum zeylanicum) is used extensively as an antimicrobial material and currently is being increasingly used in Europe by people with type II diabetes to control their glucose levels.
Henken, Rachel L., Kamatou, Guy P, Viljoen, Alvaro M, Kamatou, Guy P. P., Gilman, S. Douglass, Viljoen, Alvaro M., Waldrop, Grover L, Rahman, Md Mukhlesur, Gilman, S Douglass, Waldrop, Grover L., Kamatou, Guy P.P., Gibbons, Simon, Henken, Rachel L, Meades, Glen   +13 more
core   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source

Insights into the methodology of acetyl-CoA carboxylase inhibition

Acetyl-CoA carboxylase catalyzes the first committed and regulated step in fatty acid synthesis in all animals, plants and bacteria. In most Gram-positive and Gram-negative bacteria, the enzyme is composed of three proteins: biotin carboxylase, biotin ...
Larson, Brent A., Waldrop, Grover L., Čavužić, Mirela Tkalčić   +2 more
core   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

Acetyl-CoA carboxylase maintains energetic balance for functional oogenesis

Nature Communications
Reproduction is tightly linked to nutrient availability and metabolic homeostasis, yet how specific metabolic pathways coordinate with cellular signaling to control oogenesis remains unclear.
Oyundari Amartuvshin, Chi-Hung Lin, Yi-Ting Ke, Han-Jung Lee, Kreeti Kajal, Tsai-Ling Huang, Wen-Der Wang, Tsai-Ming Lu, Ling-Huei Yih, Chen-Yuan Tseng, Hwei-Jan Hsu   +10 more
doaj   +1 more source

Piperazine Oxadiazole Inhibitors of Acetyl-CoA Carboxylase

, 2016
Acetyl-CoA carboxylase (ACC) is a target of interest for the treatment of metabolic syndrome. Starting from a biphenyloxadiazole screening hit, a series of piperazine oxadiazole ACC inhibitors was developed.
Kevin Salyers (1533250), Michael D. Bartberger (1635574), Hong Shu (542437), James Meyer (1864831), Christopher Fotsch (1261629), Ki-Won Kim (833560), Matthew P. Bourbeau (1261632), Renee Komorowski (405305), Minghan Wang (328553), Yang Xu (178421), Murielle M. Véniant (1864825), Melissa Graham (1864840), James Busby (1864828), Wei Gu (26249), John G. Allen (1864834), Aaron Siegmund (1822093), Mark Fielden (1864837)   +16 more
core   +1 more source