Results 91 to 100 of about 42,990 (270)

Primary structure of the biotin-binding site of chicken liver acetyl-CoA carboxylase

, 1987
Limited proteolysis of chicken liver acetyl-CoA carboxylase by staphylococcal serine proteinase yielded a fragment of 31 kDa which contained the biotinyl active site.
Tanabe, Tadashi, Toshiyuki Takai, Kenji Wada, Takai, Toshiyuki, Tadashi Tanabe, Wada, Kenji   +5 more
core   +1 more source

Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival

Nature Communications, 2017
The lipogenic pathway is often upregulated in liver tumours and regarded as a therapeutic target. Here, the authors show instead that blocking lipogenesis via knockout of acetyl-CoA carboxylase genes results in increased susceptibility to liver ...
Marin E. Nelson, Sujoy Lahiri, Jenny D. Y. Chow, Frances L. Byrne, Stefan R. Hargett, David S. Breen, Ellen M. Olzomer, Lindsay E. Wu, Gregory J. Cooney, Nigel Turner, David E. James, Jill K. Slack-Davis, Carolin Lackner, Stephen H. Caldwell, Kyle L. Hoehn   +14 more
doaj   +1 more source

Energy stress inhibits ferroptosis via AMPK

Molecular & Cellular Oncology, 2020
Energy stress disturbs cellular homeostasis and induces cell death. Our recent study revealed that ferroptosis (a non-apoptotic cell death) is an energy-requiring process, and energy stress-mediated activation of adenosine monophosphate-activated protein
Hyemin Lee, Li Zhuang, Boyi Gan
doaj   +1 more source

Essential oils as bioherbicides: effects of orange and citronella oils on weed germination and early growth

Pest Management Science, EarlyView.
Essential oils from orange and citronella showed dose‐dependent inhibition of weed germination and early growth, highlighting their potential as bioherbicides and sustainable tools for integrated weed management. Abstract BACKGROUND Increasing selection of herbicide‐resistant weed biotypes has intensified the search for alternatives to the intensive ...
Geovana Rocha Marzochi, Leonardo de Oliveira Semensato, Francielli Santos de Oliveira, Virginia Claudia Paulino Silva, Eliane Gomes Fabri, Evandro Henrique Schinor, Andréia Cristina Silva Hirata, Moacir Rossi Forim, Angélica Correa Kauffmann, Patricia Andrea Monquero   +9 more
wiley   +1 more source

De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages

Frontiers in Immunology, 2018
Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, is able to efficiently manipulate the host immune system establishing chronic infection, yet the underlying mechanisms of immune evasion are not fully understood.
Philipp Stüve, Lucía Minarrieta, Hanna Erdmann, Catharina Arnold-Schrauf, Maxine Swallow, Melanie Guderian, Freyja Krull, Alexandra Hölscher, Peyman Ghorbani, Jochen Behrends, Wolf-Rainer Abraham, Christoph Hölscher, Tim D. Sparwasser, Luciana Berod   +13 more
doaj   +1 more source

Pro‐197 mutations confer resistance to thiencarbazone but not to foramsulfuron in ALS‐resistant Poa annua populations

Pest Management Science, EarlyView.
Foramsulfuron remains effective on Pro‐197 Poa annua, but co‐formulation with thiencarbazone reduces efficacy due to limited activity and antagonism. Therefore, foramsulfuron + thiencarbazone should be used in fields without ALS‐resistant weeds to ensure effective in‐crop control.
Vijaya Bhaskar Alwarnaidu Vijayarajan, Iniya Vijayakumar, Rafa Ruiz‐Partida, Fabian Runge, Joel Torra, Jorge Lozano‐Juste, Patrick Dermot Forristal   +6 more
wiley   +1 more source

Study of the Effect of N-terminal mEGFP Tagging on the Enzymatic Activity and Cellular Localization of Human Acetyl-CoA Carboxylase 1

, 2023
Acetyl-CoA carboxylase 1 is the rate-limiting enzyme of fatty acid synthesis. It carboxylates acetyl-CoA to form malonyl-CoA in an ATP-dependent manner.
Zhang, Linsheng
core   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Constituents of cinnamon inhibit bacterial acetyl CoA carboxylase

, 2010
Cinnamon bark (Cinnamomum zeylanicum) is used extensively as an antimicrobial material and currently is being increasingly used in Europe by people with type II diabetes to control their glucose levels.
Henken, Rachel L., Kamatou, Guy P, Viljoen, Alvaro M, Kamatou, Guy P. P., Gilman, S. Douglass, Viljoen, Alvaro M., Waldrop, Grover L, Rahman, Md Mukhlesur, Gilman, S Douglass, Waldrop, Grover L., Kamatou, Guy P.P., Gibbons, Simon, Henken, Rachel L, Meades, Glen   +13 more
core   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source