Results 101 to 110 of about 42,990 (270)

We set the objective function of the constructed models to the given reactions (acetyl-CoA synthetase and acetyl-CoA carboxylase reactions) and turned the lower bound to zero for maximizing the production and regulation reaction of acetyl-CoA.

open access: yes, 2014
The producing reaction of acetyl-CoA is catalyzed by acetyl-CoA synthetase, which is in turn regulated by acetyl-CoA carboxylase, an enzyme which catalyzes acetyl CoA conversion to malonyl-CoA, the first and rate-limiting reaction in de novo synthesis of
Ali Akbar Saboury (233129)   +3 more
core   +1 more source

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

open access: yesJournal of Lipid Research, 1975
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj   +1 more source

Monitoring spirodiclofen resistance in female Brevipalpus yothersi (Acari: Tenuipalpidae) from citrus orchards in Southeastern Brazil

open access: yesAgricultural and Forest Entomology, EarlyView.
Spirodiclofen resistance levels in B. yothersi varied geographically across the Brazilian citrus belt, with higher resistance in the central region. Sublethal effects included reduced oviposition, increased non‐viable eggs and disrupted female reproduction.
Hector Alonso Escobar‐Garcia   +1 more
wiley   +1 more source

Measurement of acetyl-CoA carboxylase activity in isolated hepatocytes

open access: yes, 1987
An assay is described for acetyl-CoA carboxylase activity in isolated hepatocytes. The assay is based on two principles: (a) The hepatocytes are made permeable by digitonin.
Bijleveld, C., Geelen, M.J.H.
core   +1 more source

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

Rapid induction of hepatic acetyl-CoA carboxylase activity after estradiol benzoate injection in the quail

open access: yes, 1981
The time course of hepatic Acetyl-CoA carboxylase activity as well as hepatic and plasmatic fatty acids concentrations following a single injection of estradiol benzoate (EB, 0.2 mg/kg) was studied in the quail.
Pageaux, Jean François   +5 more
core   +1 more source

Iterative cycle of widely targeted metabolic profiling for the improvement of 1-butanol titer and productivity in Synechococcus elongatus

open access: yesBiotechnology for Biofuels, 2018
Background Metabolomics is the comprehensive study of metabolites that can demonstrate the downstream effects of gene and protein regulation, arguably representing the closest correlation with phenotypic features.
Artnice Mega Fathima   +5 more
doaj   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

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