Results 121 to 130 of about 43,087 (252)

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

THE PURIFICATION AND PROPERTIES OF ACETYL-COENZYME A CARBOXYLASE KINASE [PDF]

open access: yes, 1982
Acetyl-CoA carboxylase kinase has been purified to apparent homogeneity from rat liver. The kinase was found to exist in two forms: bound to carboxylase in a complex or in a free form that is in different stages of aggregation over a wide range of ...
LENT, BRUCE ALAN
core  

4‐1BBL Suppresses Anti‐Inflammatory Responses by Regulating Metabolic Reprogramming of Macrophages

open access: yesImmunology, EarlyView.
4‐1BB ligand (4‐1BBL) is known to promote sustained pro‐inflammatory responses in macrophages. This study demonstrates that 4‐1BBL acts as a negative regulator of anti‐inflammatory macrophage responses. Genetic deletion or pharmacological inhibition of 4‐1BBL significantly enhanced the phosphorylation of IL‐4R‐proximal JAK1 and STAT6, elevating the ...
Young Jun Kang
wiley   +1 more source

Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase [PDF]

open access: yes, 1997
Rasmussen, B. B., and W. W. Winder. Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. J. Appl. Physiol. 83(4): 1104–1109, 1997.—Malonyl-CoA is synthesized by acetyl-CoA carboxylase (ACC) and is an inhibitor of fatty ...
W. W. Winder, B. B. Rasmussen
core   +1 more source

Orchid genome evolution and trait innovation

open access: yesJournal of Integrative Plant Biology, EarlyView.
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng   +8 more
wiley   +1 more source

Overlooked components of lipid metabolism: Odd‐chain polyunsaturated fatty acids in photosynthetic microorganisms

open access: yesJournal of Phycology, EarlyView.
Abstract This mini‐review examines odd‐carbon polyunsaturated fatty acids (odd‐PUFAs), a rare but biologically significant group of fatty acids in photosynthetic microorganisms. Odd‐PUFAs are straight‐chain fatty acids containing an odd number of carbon atoms and two or more methylene‐interrupted double bonds. They typically account for less than 1% of
Linda Nedbalová   +2 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

Disruption of starch biosynthesis and triacylglycerol degradation impairs growth but improves photosynthesis in Arabidopsis

open access: yesNew Phytologist, EarlyView.
Proposed model for altered carbon partitioning in wild‐type (a) and tgd1 sdp1 adg1‐1 Arabidopsis triple mutant (b). Summary Enhancing lipid accumulation by redirecting carbon from starch to triacylglycerol (TAG) in vegetative tissues is a promising strategy for developing high‐energy‐density crops for bioenergy production. However, our understanding of
Jilian Fan   +5 more
wiley   +1 more source

Studies of acetyl-CoA carboxylase gene expression [PDF]

open access: yes, 1993
Acetyl-Coenzyme A carboxylase (ACC; acetyl-CoA:carbon dioxide ligase (ADP forming), EC 6.4.1.2) catalyzes the first committed step in the biosynthesis of long-chain fatty acids. The construction of ribozyme genes that are designed to hydrolyze acetyl-CoA
Ha, Joohun
core  

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

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