Results 141 to 150 of about 56,989 (293)

Capsaicinoid Glucoside Attenuates Lipid Accumulation in HepG2 Cells Through TRPV1/AMPK‐Dependent Signaling Pathway

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
Capsaicinoid glucoside (CG), reduces triglyceride (TG) and total cholesterol (TC) accumulation in OA‐treated HepG2 cells. CG alleviates reactive oxygen species (ROS) and enhancing lipid oxidation. CG activates the TRPV1/AMPK pathway, while downregulating the expression of lipogenic genes SREBP‐1C and FAS.
Abdeen Elkhedir   +8 more
wiley   +1 more source

Variation in Acetyl-CoA Carboxylase Beta Gene and Its Effect on Carcass and Meat Traits in Gannan Yaks. [PDF]

open access: yesInt J Mol Sci, 2023
Zhu C   +11 more
europepmc   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 7, Page 850-859, July 2025.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis   +5 more
wiley   +1 more source

Efficacy of Haloxyfop‐R‐Methyl on Allium cepa: Cyto‐Genotoxic and In Silico Docking Studies on the Mechanism of Action

open access: yesMicroscopy Research and Technique, Volume 88, Issue 7, Page 2048-2062, July 2025.
ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman   +4 more
wiley   +1 more source

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

open access: yesJournal of Lipid Research, 1975
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj  

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