Results 161 to 170 of about 56,989 (293)

Clearance of Hepatitis C Viremia During Direct‐Acting Antiviral Therapy Leads to Rapid Changes in Lipid and Lipoprotein Metabolism

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 2, Page 146-158, July 2025.
HCV clearance during direct‐acting antiviral therapy rapidly increases serum lipids and lipoproteins, potentially elevating cardiovascular risk. These metabolic changes, mediated by genes regulating hepatic lipogenesis, suggest that lipid levels should be closely monitored post‐SVR to assess long‐term cardiovascular implications.
Zahra Sarrafan‐Chaharsoughi   +12 more
wiley   +1 more source

Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit? [PDF]

open access: yesWorld J Gastroenterol, 2021
Neokosmidis G   +2 more
europepmc   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, Volume 58, Issue 7, July 2025.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

Cytokinesis‐Defective 1 (CYT1) Positively Regulates Plant Antiviral Immunity by Promoting Callose Deposition and Ascorbic Acid Biosynthesis

open access: yesMolecular Plant Pathology, Volume 26, Issue 7, July 2025.
Turnip mosaic virus (TuMV)‐encoded NIb protein interacts with CYT1 to reduce callose deposition and ascorbic acid biosynthesis, while promoting N‐linked glycosylation to enable robust infection. ABSTRACT NUCLEAR INCLUSION B (NIb), the RNA‐dependent RNA polymerase (RdRp) of potyviruses, plays a critical role in both viral replication and suppression of ...
Xue Jiang   +12 more
wiley   +1 more source

Receptor‐like kinases BIR1 and BIR3 modulate antiviral resistance by different mechanisms

open access: yesNew Phytologist, Volume 247, Issue 2, Page 813-829, July 2025.
Summary BRASSINOSTEROID INSENSITIVE1‐ASSOCIATED RECEPTOR KINASE 1 (BAK1)‐INTERACTING RECEPTOR‐LIKE KINASE (BIR) proteins are negative regulators of cell death and defense against microbes in Arabidopsis thaliana. Here, we demonstrate that the members of the BIR family function as negative regulators of antiviral resistance in Arabidopsis.
Carmen Robinson   +8 more
wiley   +1 more source

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