Results 181 to 190 of about 86,728 (368)

Cover 3 - Acetyl-CoA Carboxylase Inhibition Has Multimodal Effects in NASH

, 2020

openalex   +1 more source

Figure S2 from Phosphorylated Acetyl-CoA Carboxylase Is Associated with Clinical Benefit with Regorafenib in Relapsed Glioblastoma: REGOMA Trial Biomarker Analysis

, 2023
Stefano Indraccolo, Gian Luca De Salvo, Martina Verza, Mario Caccese, Giovanni Esposito, Ilaria Piga, Paola Del Bianco, Marco Pizzi, Marina Paola Gardiman, Marica Eoli, Roberta Rudà, Alba A. Brandes, Toni Ibrahim, Simona Rizzato, Ivan Lolli, Vittorina Zagonel, Giuseppe Lombardi   +16 more
openalex   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.

Cell Metabolism, 2019
J. Lally, Sarani Ghoshal, D. DePeralta, O. Moaven, Lan Wei, Ricard Masia, Derek J. Erstad, N. Fujiwara, Vivian Leong, Vanessa P. Houde, Alexander E. Anagnostopoulos, Alice Wang, Lindsay A. Broadfield, R. Ford, R. Foster, J. Bates, H. Sun, Ting Wang, Henry Liu, A. Ray, A. Saha, J. Greenwood, Sathesh Bhat, G. Harriman, Wenyan Miao, J. Rocnik, W. Westlin, P. Muti, T. Tsakiridis, H. J. Harwood, R. Kapeller, Y. Hoshida, K. Tanabe, G. Steinberg, B. Fuchs   +34 more
semanticscholar   +1 more source

The multifaceted roles of ketones in physiology

Experimental Physiology, EarlyView.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Magnus J. Stenlund, John R. Ussher   +3 more
wiley   +1 more source

Purification and properties of a kinase which phosphorylates and inactivates acetyl-CoA carboxylase.

, 1982
Bruce A. Lent, K H Kim
openalex   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase and Mechanism of Action for the Antibacterial Agent Moiramide B

, 2014
Molly A. Silvers
openalex   +2 more sources

Dephosphorylation and activation of Acetyl‐CoA‐carboxylase from lactating rabbit mammary gland [PDF]

, 1979
D. Grahame Hardie, Philip Cohen
openalex   +1 more source

Paired related homeobox 1 attenuates autophagy via acetyl‐CoA carboxylase 1‐regulated fatty acid metabolism in salivary adenoid cystic carcinoma

, 2022
Jie Gao, Kangjie Ma, Li Zhang, Tao Li, Baodong Zhao, Yaping Jiang, Jie Gao, Kangjie Ma, Li Zhang, Tao Li, Baodong Zhao, Yaping Jiang   +11 more
openalex   +1 more source