Results 51 to 60 of about 56,101 (298)

Investigation of acetyl-CoA carboxylase-inhibiting herbicides that exhibit soybean crop selectivity. [PDF]

Pest Manag Sci
The work presented herein details our approaches for the optimization of structural features that display soybean crop selectivity amongst the aryl‐KTE class of ACCase‐inhibiting herbicides. It is foreseen that utilizing such approaches will facilitate the acceleration of crop protection optimization programmes, as well as enabling the more sustainable
Lee S, Payne C, Rees S, Ahrens H, Arve L, Asmus E, Bojack G, Arsequell EB, Gatzweiler E, Helmke H, Kallus C, Laber B, Lange G, Lehr S, Menne H, Rosinger CH, Schulte W, Sommer K, Barber DM.   +18 more
europepmc   +2 more sources

Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.

Journal of the American Society of Nephrology, 2018
BACKGROUND Expression of genes regulating fatty acid metabolism is reduced in tubular epithelial cells from kidneys with tubulointerstitial fibrosis (TIF), thus decreasing the energy produced by fatty acid oxidation (FAO). Acetyl-CoA carboxylase (ACC), a
Mardiana Lee, M. Katerelos, Kurt Gleich, S. Galic, B. Kemp, P. Mount, D. Power   +6 more
semanticscholar   +1 more source

CYP81A P450s are involved in concomitant cross-resistance to acetolactate synthase and acetyl-CoA carboxylase herbicides in Echinochloa phyllopogon.

New Phytologist, 2018
Californian populations of Echinochloa phyllopogon have evolved multiple-herbicide resistance (MHR), posing a threat to rice production in California.
S. Iwakami, Yoshitaka Kamidate, Takuya Yamaguchi, M. Ishizaka, M. Endo, Hiroe Suda, Kiichi Nagai, Y. Sunohara, S. Toki, A. Uchino, T. Tominaga, H. Matsumoto   +11 more
semanticscholar   +1 more source

Metabolic Engineering of Pichia pastoris for the Production of Triacetic Acid Lactone

Journal of Fungi, 2023
Triacetic acid lactone (TAL) is a promising renewable platform polyketide with broad biotechnological applications. In this study, we constructed an engineered Pichia pastoris strain for the production of TAL.
Linjuan Feng, Junhao Xu, Cuifang Ye, Jucan Gao, Lei Huang, Zhinan Xu, Jiazhang Lian   +6 more
doaj   +1 more source

AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis

eLife, 2018
AMP-activated protein kinase (AMPK) is a known regulator of whole-body energy homeostasis, but the downstream AMPK substrates mediating these effects are not entirely clear.
S. Galic, K. Loh, L. Murray‐Segal, G. Steinberg, Z. Andrews, B. Kemp   +5 more
semanticscholar   +1 more source

Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA

Computational and Structural Biotechnology Journal, 2022
Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids ...
Humberto Pereira, Flávio Azevedo, Lucília Domingues, Björn Johansson   +3 more
doaj  

Cloning of human acetyl‐CoA carboxylase cDNA [PDF]

European Journal of Biochemistry, 1994
Acetyl‐CoA carboxylase is the rate‐limiting enzyme in the biogenesis of long‐chain fatty acids. In order to understand the mechanisms that regulate human acetyl‐CoA carboxylase at the gene level, and the relationship between its structure and function, cDNA clones for human acetyl‐CoA carboxylase have been isolated and sequenced.
Ki-Han Kim, Hyi-Jeong Tae, Samira Daniel, In-Soo Kong, Chung-Kil Park, Joohun Ha   +5 more
openaire   +3 more sources

In silico identification of potential inhibitors of acyl carrier protein reductase and acetyl CoA carboxylase of Plasmodium falciparum in antimalarial therapy

Frontiers in Drug Discovery, 2023
Malaria caused by Plasmodium falciparum, remains one of the most fatal parasitic diseases that has affected nearly a third of the world’s population. The major impediment to the treatment of malaria is the emergence of resistance of the P.
Elliasu Y. Salifu, James Abugri, James Abugri, Issahaku A. Rashid, Festus Osei, Joseph Atia Ayariga   +5 more
doaj   +1 more source

High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5′-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase (*)

Journal of Biological Chemistry, 1995
We determined whether high fatty acid oxidation rates during aerobic reperfusion of ischemic hearts could be explained by a decrease in malonyl-CoA levels, which would relieve inhibition of carnitine palmitoyltransferase 1, the rate-limiting enzyme ...
Naomi Kudo, A. Barr, R. Barr, Snehal Desai, G. Lopaschuk   +4 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source