Results 51 to 60 of about 35,842 (269)
Frontiers in Microbiology, 2016 The family of PII signal transduction proteins (members GlnB, GlnK, NifI) plays key roles in various cellular processes related to nitrogen metabolism at different functional levels.
Waldemar Hauf +5 more
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Sequences of acetyl CoA carboxylase promoter for tumour necrosis factor action
Mediators of Inflammation, 1993 Tumour necrosis factor (TNF) inhibits the accumulation of acetyl CoA carboxylase (ACC) mRNA by decreasing the rate of ACC gene transcription. The ACC mRNA species found in 30A5 cells are generated from promoter II and TNF inhibits the accumulation of ...
Keerang Park +2 more
doaj +1 more source
Phosphorylation of pea chloroplast acetyl‐CoA carboxylase [PDF]
The Plant Journal, 1999 SummaryWe have examined whether chloroplast acetyl‐CoA carboxylase is a phosphoprotein. Pea (Pisum sativum) chloroplasts were incubated in the presence of [γ‐33P]‐ATP and radiolabeled proteins were examined after immunoprecipitation with antibodies against all four known subunits of heteromeric chloroplast acetyl‐CoA carboxylase.
John B. Ohlrogge, Linda J. Savage
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Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase.
PLoS ONE, 2020 Antimicrobial resistance is a growing global health and economic concern. Current antimicrobial agents are becoming less effective against common bacterial infections.
Erica C Larson +7 more
doaj +1 more source
Key Molecules of Fatty Acid Metabolism in Gastric Cancer
Biomolecules, 2022 Fatty acid metabolism is closely linked to the progression of gastric cancer (GC), a very aggressive and life-threatening tumor. This study examines linked molecules, such as Sterol Regulatory Element-Binding Protein 1 (SREBP1), ATP Citrate Lyase (ACLY),
Chunlei Li +4 more
doaj +1 more source
Food Frontiers, EarlyView.Sodium selenite or vitamin E supplementation enhances antioxidant defenses in mouse mammary glands, reducing oxidative stress, lipid peroxidation, and iron accumulation. This boosts GPX4 activity, inhibits PTGS2, and activates mTORC1, improving milk fat droplet formation and protein synthesis, with the combined treatment showing the greatest benefit ...
Qianzi Zhang +7 more
wiley +1 more source
The Regulatory Effects of Acetyl-CoA Distribution in the Healthy and Diseased Brain
Frontiers in Cellular Neuroscience, 2018 Brain neurons, to support their neurotransmitter functions, require a several times higher supply of glucose than non-excitable cells. Pyruvate, the end product of glycolysis, through pyruvate dehydrogenase complex reaction, is a principal source of ...
Anna Ronowska +7 more
doaj +1 more source
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
Bimodal Activation of Acetyl-CoA Carboxylase by Glutamate [PDF]
Journal of Biological Chemistry, 2000 Acetyl-CoA carboxylase (ACC) catalyzes the formation of malonyl-CoA, an essential substrate for fatty acid biosynthesis and a potent inhibitor of fatty acid oxidation. Here, we provide evidence that glutamate may be a physiologically relevant activator of ACC.
Jerzy E. Kulpa +3 more
openaire +3 more sources
Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing
Glia, EarlyView.Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production. ABSTRACT In the hypothalamus, detection of energy substrates such as glucose is essential to regulate ...
Sarah Geller +11 more
wiley +1 more source