Results 61 to 70 of about 35,842 (269)

Determination of the quantity of acetyl CoA carboxylase by [14C]methyl avidin binding

open access: yesJournal of Lipid Research, 1987
Conditions are described under which monomeric [14C]methyl avidin binds to SDS-denatured biotin enzymes and remains bound through polyacrylamide gel electrophoresis. The location of radioactive proteins on the dried gel was determined by fluorography and
C R Roman-Lopez, J Goodson, J B Allred
doaj   +1 more source

Cuticular waxes in alpine grassland plants: Chemical diversity, biosynthesis, and ecological adaptation with biotechnological insights

open access: yesGrassland Research, EarlyView.
Alpine plants use specialized cuticular waxes to survive extreme cold, UV radiation, and drought. This study explores how these waxes adapt to environmental stress, revealing their chemical diversity, biosynthesis, and ecological roles. Understanding these adaptations can inspire innovations in climate‐resilient crops and UV‐protective bioproducts ...
Jiawei Xu   +4 more
wiley   +1 more source

Acetyl CoA Carboxylase: The Purified Transcarboxylase Component [PDF]

open access: yesProceedings of the National Academy of Sciences, 1971
Acetyl CoA carboxylase of Escherichia coli has been resolved into three functionally dissimilar proteins: ( 1 ) biotin-carboxyl carrier protein (BCCP); ( 2 ) a biotin carboxylase component that catalyzes the Mn-ATP-dependent carboxylation of BCCP to form CO
S G Gordon, P R Vagelos, A W Alberts
openaire   +3 more sources

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello   +7 more
wiley   +1 more source

ACCase cross-resistance in Italian ryegrass (Lolium multiflorum) sub-populations from Oregon, US

open access: yesJulius-Kühn-Archiv, 2012
ACCase-resistant Italian ryegrass (Lolium multiflorum) is one of the most troublesome weeds in US wheat production systems. This study had the objective of determining the resistance pattern of three subpopulations selected from a winter wheat field with
Barbosa Martins, Bianca Assis   +3 more
doaj   +1 more source

LRP8 Regulates Lipid Metabolism to Stimulate Malignant Progression and Cisplatin Resistance in Bladder Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Low‐density lipoprotein receptor‐related protein 8 (LRP8) is a crucial regulator of lipid metabolism and is implicated in the development and treatment of various cancers. However, its role in bladder cancer (BCa) remains unknown. We analyzed LRP8 expression in BCa using the TCGA database and clinical samples. We manipulated LRP8 expression in
Gang‐Feng Wu   +5 more
wiley   +1 more source

Elevating acetyl-CoA levels reduces aspects of brain aging

open access: yeseLife, 2019
Because old age is the greatest risk factor for dementia, a successful therapy will require an understanding of the physiological changes that occur in the brain with aging. Here, two structurally distinct Alzheimer's disease (AD) drug candidates, CMS121
Antonio Currais   +8 more
doaj   +1 more source

Ferroptosis in Pneumoconiosis: From Molecular and Cellular Mechanisms to Therapeutic Strategies

open access: yesMed Research, EarlyView.
Targeting lung various cells to alleviate pneumoconiosis by suppressing ferroptosis. AAV9‐HGF, adeno‐associated virus‐hepatocyte growth factor; DFP, deferiprone; DHQ, dihydroquercetin; Fer‐1, ferrostatin‐1; IL‐1β, interleukin‐1β; NMN, nicotinamide mononucleotide; sh‐SLC39A14, shRNA targeting solute carrier family 39 member 14; si‐OC‐STAMP, siRNA ...
Mengli Yan   +4 more
wiley   +1 more source

Insights into ALS‐inhibiting herbicide resistance in Poa annua in an arable cropping system

open access: yesPest Management Science, EarlyView.
Variable cross‐resistance to ALS inhibitors in five Poa annua populations from wheat fields in Ireland caused by different TSR mutations. Abstract BACKGROUND Dependence on a single herbicide type to control a broad‐spectrum of weeds has resulted in cases of resistance to acetolactate synthase (ALS) inhibitors in weeds normally considered lower priority
Alwarnaidu Vijayarajan Vijaya Bhaskar   +5 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

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