Results 61 to 70 of about 86,728 (368)

Elucidating fish oil-induced milk fat depression in dairy sheep: Milk somatic cell transcriptome analysis [PDF]

open access: yes, 2017
9 páginas, 4 figuras.In this study, RNA sequencing was used to obtain a comprehensive profile of the transcriptomic changes occurring in the mammary gland of lactating sheep suffering from fish oil-induced milk fat depression (FO-MFD).
Arranz, Juan José   +5 more
core   +1 more source

CYP81A P450s are involved in concomitant cross-resistance to acetolactate synthase and acetyl-CoA carboxylase herbicides in Echinochloa phyllopogon.

open access: yesNew Phytologist, 2018
Californian populations of Echinochloa phyllopogon have evolved multiple-herbicide resistance (MHR), posing a threat to rice production in California.
S. Iwakami   +11 more
semanticscholar   +1 more source

Metabolic Engineering of Pichia pastoris for the Production of Triacetic Acid Lactone

open access: yesJournal of Fungi, 2023
Triacetic acid lactone (TAL) is a promising renewable platform polyketide with broad biotechnological applications. In this study, we constructed an engineered Pichia pastoris strain for the production of TAL.
Linjuan Feng   +6 more
doaj   +1 more source

The subcellular localization of acetyl-CoA carboxylase 2 [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
Animals, including humans, express two isoforms of acetyl-CoA carboxylase (EC 6.4.1.2 ), ACC1 ( M r = 265 kDa) and ACC2 ( M r = 280 kDa). The predicted amino acid sequence of ACC2 contains an additional 136 aa relative to ACC1, 114 of which ...
L, Abu-Elheiga   +5 more
openaire   +2 more sources

In silico identification of potential inhibitors of acyl carrier protein reductase and acetyl CoA carboxylase of Plasmodium falciparum in antimalarial therapy

open access: yesFrontiers in Drug Discovery, 2023
Malaria caused by Plasmodium falciparum, remains one of the most fatal parasitic diseases that has affected nearly a third of the world’s population. The major impediment to the treatment of malaria is the emergence of resistance of the P.
Elliasu Y. Salifu   +5 more
doaj   +1 more source

Complex formation and regulation of Escherichia coli acetyl-CoA carboxylase [PDF]

open access: yes, 2013
Acetyl-CoA carboxylase is a biotin-dependent, multifunctional enzyme that catalyzes the first committed step in fatty acid synthesis. The Escherichia coli enzyme is composed of a homodimeric biotin carboxylase, biotinylated biotin carboxyl carrier ...
Broussard, Tyler Craig
core   +2 more sources

Cloning of human acetyl‐CoA carboxylase cDNA [PDF]

open access: yesEuropean Journal of Biochemistry, 1994
Acetyl‐CoA carboxylase is the rate‐limiting enzyme in the biogenesis of long‐chain fatty acids. In order to understand the mechanisms that regulate human acetyl‐CoA carboxylase at the gene level, and the relationship between its structure and function, cDNA clones for human acetyl‐CoA carboxylase have been isolated and sequenced.
J, Ha   +5 more
openaire   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Long noncoding RNA ZFP36L2-AS functions as a metabolic modulator to regulate muscle development

open access: yesCell Death and Disease, 2022
Skeletal muscle is the largest metabolic organ in the body, and its metabolic flexibility is essential for maintaining systemic energy homeostasis. Metabolic inflexibility in muscles is a dominant cause of various metabolic disorders, impeding muscle ...
Bolin Cai   +10 more
doaj   +1 more source

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