Results 161 to 170 of about 118,012 (240)

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design. [PDF]

Nat Commun, 2019
Lu X, Liu Y, Yang Y, Wang S, Wang Q, Wang X, Yan Z, Cheng J, Liu C, Yang X, Luo H, Yang S, Gou J, Ye L, Lu L, Zhang Z, Guo Y, Nie Y, Lin J, Li S, Tian C, Cai T, Zhuo B, Ma H, Wang W, Ma Y, Liu Y, Li Y, Jiang H.   +28 more
europepmc   +1 more source

Liver Acetyl Coenzyme A Carboxylase

Journal of Biological Chemistry, 1968
C Gregolin, E Ryder, R C Warner, A K Kleinschmidt, H C Chang, M D Lane   +5 more
openaire   +2 more sources

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Staphylococcus aureus modulates the activity of acetyl-Coenzyme A synthetase (Acs) by sirtuin-dependent reversible lysine acetylation. [PDF]

Mol Microbiol, 2019
Burckhardt RM, Buckner BA, Escalante-Semerena JC.   +2 more
europepmc   +1 more source

Metabolic Reprogramming and Exosome Remodeling in an Ndufs4‐Deficient Model of Leigh Syndrome

iNew Medicine, Volume 2, Issue 2, June 2026.
Ndufs4 knockout drives exosomal remodeling, reprograms cellular metabolism, impairs neural stem cell self‐renewal and differentiation, and suppresses mTOR signaling, providing a conceptual framework for understanding Leigh syndrome pathogenesis and informing therapeutic development.
Yakun Liu, Zhi Yang, Zhencai Xing, Rongrong Zhao, Yixuan Zhou, Xue Yang, Jicheng Zhu, Shuo Chen, Yuhang Zhang, Mengxue Xu, Xiang Kong, Minqiong Sun, Zhenya Tan, Hong Zheng   +13 more
wiley   +1 more source

Growth of Oxygen Environment of the Newborn Vocal Fold Maculae Flavae as a Stem Cell Niche

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objectives Accumulating evidence indicates that the anterior and posterior maculae flavae of the human vocal fold mucosa function as niches for tissue stem cells. This study aimed to characterize the oxygen microenvironment of the maculae flavae in the newborn vocal fold and to clarify its potential involvement in metabolic regulation and the ...
Kiminori Sato, Shun‐ichi Chitose, Fumihiko Sato, Kiminobu Sato, Takeharu Ono, Hirohito Umeno   +5 more
wiley   +1 more source

Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models. [PDF]

Emerg Microbes Infect, 2019
Jiménez de Oya N, Esler WP, Huard K, El-Kattan AF, Karamanlidis G, Blázquez AB, Ramos-Ibeas P, Escribano-Romero E, Louloudes-Lázaro A, Casas J, Sobrino F, Hoehn K, James DE, Gutiérrez-Adán A, Saiz JC, Martín-Acebes MA.   +15 more
europepmc   +1 more source

Carboxylation of acetonyldethio‐coenzyme a by acetyl coenzyme a carboxylase

FEBS Letters, 1978
Nikawa, Jun-ichi, Numa, Shosaku, Shiba, Tetsuo, Stewart, Charles J., Wieland, Theodor   +4 more
openaire   +2 more sources

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang, Chenyang Mu, Rui Zhao, Runwei Ma, Xuehai Liu, Haoling Zhang, Zengwu Wang, Jing‐jing Zhang   +7 more
wiley   +1 more source

N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines. [PDF]

J Oncol, 2019
Stepp MW, Salazar-González RA, Hong KU, Doll MA, Hein DW.   +4 more
europepmc   +1 more source