Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Ferroptosis is a form of programmed cell death characterized by iron‐dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this process.
Xiaoqian Tang +5 more
wiley +1 more source
Staphylococcus aureus modulates the activity of acetyl-Coenzyme A synthetase (Acs) by sirtuin-dependent reversible lysine acetylation. [PDF]
Mol Microbiol, 2019 Burckhardt RM +2 more
europepmc +1 more source
Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska +5 more
wiley +1 more source
Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models. [PDF]
Emerg Microbes Infect, 2019 Jiménez de Oya N +15 more
europepmc +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.Paeonol protects against cisplatin‐ and noise‐induced hearing loss by mitigating oxidative damage and preserving protein homeostasis in cochlear hair cells, revealing a novel mechanism involving ribosome biogenesis. ABSTRACT Background Hearing loss primarily results from irreversible cochlear hair cell (HC) damage caused by factors such as noise, aging,
Minhui Xia +8 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley +1 more source
Acetyl-coenzyme A synthetase gene ChAcs1 is essential for lipid metabolism, carbon utilization and virulence of the hemibiotrophic fungus Colletotrichum higginsianum. [PDF]
Mol Plant Pathol, 2019 Gu Q +6 more
europepmc +1 more source
Food Science &Nutrition, Volume 14, Issue 9, September 2026.These findings demonstrate that with adequate protein intake, graded short‐term EL (20%–40%) effectively improves hepatic lipid metabolism and modulates gut microbiota composition in overweight/obese mice, although these regulatory effects exhibit pronounced sex‐specific differences.
Ying Tian +6 more
wiley +1 more source
N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines. [PDF]
J Oncol, 2019 Stepp MW +4 more
europepmc +1 more source
Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia
Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang +13 more
wiley +1 more source