Results 21 to 30 of about 113,959,850 (208)

De novo fatty acid synthesis and elongation of fatty acids by subcellular fractions of lung

Journal of Lipid Research, 1971
Fatty acid synthesis by subcellular fractions of rabbit lung was studied by measuring the incorporation of either radioactive acetyl coenzyme A or malonyl coenzyme A into long-chain fatty acids.
HARVEY SCHILLER, KLAUS BENSCH
doaj   +1 more source

The dynamic organization of fungal acetyl-CoA carboxylase [PDF]

, 2016
Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of ...
Hagmann, Anna, Imseng, Stefan, Hunkeler, Moritz, Stuttfeld, Edward, Maier, Timm   +4 more
core   +1 more source

Structure, activity, and inhibition of the Carboxyltransferase β-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis. [PDF]

Antimicrob Agents Chemother, 2014
In Mycobacterium tuberculosis, the carboxylation of acetyl coenzyme A (acetyl-CoA) to produce malonyl-CoA, a building block in long-chain fatty acid biosynthesis, is catalyzed by two enzymes working sequentially: a biotin carboxylase (AccA) and a ...
Reddy MC, Breda A, Bruning JB, Sherekar M, Valluru S, Thurman C, Ehrenfeld H, Sacchettini JC.   +7 more
europepmc   +2 more sources

Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells

Journal of Lipid Research, 2006
The purpose of this study was to investigate the effects of long-chain fatty acids (LCFAs) on AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC) phosphorylation and β-oxidation in skeletal muscle.
S. Fediuc, M.P. Gaidhu, R.B. Ceddia
doaj   +1 more source

Intestinal Population in Host with Metabolic Syndrome during Administration of Chitosan and Its Derivatives

Molecules, 2020
Chitosan and its derivatives can alleviate metabolic syndrome by different regulation mechanisms, phosphorylation of AMPK (AMP-activated kinase) and Akt (also known as protein kinase B), suppression of PPAR-γ (peroxisome proliferator-activated receptor-γ)
Chen Yan, Cuili Zhang, Xuejiao Cao, Bin Feng, Xinli Li   +4 more
doaj   +1 more source

Creation of Germplasm Resources of Two-line Sterile Rice Resistant to ACCase-inhibiting Herbicides [PDF]

中国水稻科学
【Objective】The creation of herbicide-resistant rice germplasm is essential for breeding new herbicide-resistant rice varieties. By using CRISPR/Cas9 gene editing technology, the acetyl-CoA carboxylase OsACC1 gene was edited with the sterile line An 9S as
GUO Jinmeng, TAO Kailiang, ZHU Jun, ZHAO Xueyu, LI Kang, GAN Quan, LIN Cuixiang, WANG Nansheng, YU Hao, SONG Fengshun, LI Juan, SHI Yingyao, NI Dahu
doaj   +1 more source

Tissue Distribution of Acetyl-Coenzyme A Carboxylase in Leaves [PDF]

Plant Physiology, 1984
Acetyl-CoA carboxylase [acetyl-CoA-carbon dioxide ligase (ADP forming), EC 6.4.1.2] is a biotin-containing enzyme catalyzing the formation of malonyl-CoA. The tissue distribution of this enzyme was determined for leaves of C(3)- and C(4)-plants. The mesophyll tissues of the C(3)-plants Pisum sativum and Allium porrum contained 90% of the leaf acetyl ...
B J, Nikolau, E S, Wurtele, P K, Stumpf
openaire   +2 more sources

Culture Conditions Affect Antioxidant Production, Metabolism and Related Biomarkers of the Microalgae Phaeodactylum tricornutum

Antioxidants, 2022
Phaeodactylum tricornutum (Bacillariophyta) is a worldwide-distributed diatom with the ability to adapt and survive in different environmental habitats and nutrient-limited conditions.
Eleonora Curcuraci, Simona Manuguerra, Concetta Maria Messina, Rosaria Arena, Giuseppe Renda, Theodora Ioannou, Vito Amato, Claire Hellio, Francisco J. Barba, Andrea Santulli   +9 more
doaj   +1 more source

Significance of abnormal expression of fatty acid metabolic enzymes in the diagnosis of autism [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate the significance of expression level of fatty acid metabolic enzymes in the diagnosis of autism. Methods The protein content of fatty acid synthase (FASN), acetyl-CoA carboxylase (ACC), acetyl-CoA synthase 1 (AceCS1) and long ...
CHEN Jian-ling, FU Ying-mei, YU Shun-ying, CHEN Jing, DU Ya-song
doaj  

Physiological and Genetic Regulation for High Lipid Accumulation by Chlorella sorokiniana Strains from Different Environments of an Arctic Glacier, Desert, and Temperate Lake under Nitrogen Deprivation Conditions

Microbiology Spectrum, 2022
Microalgae can adapt to extreme environments with specialized metabolic mechanisms. Here, we report comparative physiological and genetic regulation analyses of Chlorella sorokiniana from different environmental regions of an arctic glacier, desert, and ...
Shanmei Zou, Zheng Huang, Xuemin Wu, Xinke Yu   +3 more
doaj   +1 more source